We report 2 cases of sacral insufficient fracture detected by FDG-PET/CT. In case 1, a 79-year-old female patient with malignant lymphoma, who had recent lumbago, received FDG-PET/CT examination. Vertical linear FDG uptake medial to bilateral sacro-iliac joint was observed on FDG-PET and a fracture line corresponding to FDG uptake was observed in bone window of CT images. In case 2, an 81-year-...

This study aimed at determining whether non attenuation corrected (NAC) positron emission tomography (PET) images, in addition to the attenuation corrected (AC) PET images, should be included in the interpretation of fluoro-18 fluorodeoxyglucose ((18)F-FDG-PET) images in patients with lymphoma. The study included 58 patients, 35 males 23 females, mean age 55+/-16 years. There were 64 superficia...

Segmentation of positron emission tomography (PET) images is a difficult task. In this study, we propose a new method for delineation of brain structures according to the tracer uptake. The method is based on a new deformable model which is particularly designed for extracting surfaces automatically from noisy images. The automation is achieved by using a global optimization algorithm for minim...

We analyzed the data for 53 patients with histologically proven primary squamous cell carcinoma of the head and neck treated with radiotherapy between February 2006 and August 2009. All patients underwent contrast-enhanced (CE)-CT and (18)F-fluorodeoxyglucose (FDG)-PET before radiation therapy planning (RTP) to define the gross tumor volume (GTV). The PET-based GTV (PET-GTV) for RTP was defined...

Understanding of standardized uptake value (SUV) of 2-deoxy-2-[18F]fluoro-d-glucose positron emission tomography (FDG-PET) depends on the background accumulations of glucose because the SUV often varies the status of patients. The purpose of this study was to develop a new method for quantitative analysis of SUV of FDG-PET scan images. The method included an anatomical standardization and a sta...

In infants, brain (18)F-FDG PET often requires sedation. To keep the sedation mild, the PET acquisition time should be kept short. Therefore, calculated attenuation correction is often preferred to measured attenuation correction. In addition, the infant should be positioned as comfortably as possible. Here, we report a case in which the infant's fist was near her head, resulting in severe arti...

The development of clinically-applicable quantitative methods for the analysis of brain fluorine-18 fluoro desoxyglucose-positron emission tomography ((18)F-FDG-PET) images is a major area of research in many neurologic diseases, particularly Alzheimer's disease (AD). Region of interest visualization, evaluation, and image registration (ROVER) is a novel commercially-available software pack...

UNLABELLED The purpose of this study was to develop a method of registering (18)F-FDG PET with MR permeability images for investigating the correlation of (18)F-FDG uptake, permeability, and cerebral blood volume (CBV) in children with pediatric brain tumors and their relationship with outcome. METHODS Twenty-four children with brain tumors in a phase II study of bevacizumab and irinotecan un...

There is a growing body of evidence for the use of FDG in the differentiation of malignant from benign disease, staging and grading of malignant disease, differentiating recurrent or residual disease from therapy induced changes, and monitoring the response to therapy. Depending on the clinical question and type of equipment available, the FDG imaging procedure may include: A. Limited Field Tom...

UNLABELLED Accurate, early differentiation of dementias will become increasingly important as new therapies are introduced. Differential diagnosis by standard clinical criteria has limited accuracy. PET offers the potential to increase diagnostic accuracy. (18)F-FDG studies detect metabolic abnormalities in demented patients, but with limited specificity. PET also offers the ability to quantify...