Extracellular vesicles, specifically microparticles (MPs), are rapidly gaining attention for their capacity to act as biomarkers for diagnosis, prognosis, or responsiveness to therapy in lung disease, in keeping with the concept of precision medicine. However, MP analysis by high-sensitivity flow cytometry (FCM) is complicated by a lack of accurate means for MP enumeration. To address this gap,...

Wujiang River, one of the main branches of the Beijiang River in South China, is frequently suffered from flood disasters. Flood clustering becomes one of the critical sub-issues for realizing the different types of flood features. This paper attempts to put forward a flood clustering approach for flood feature identification which is important to the flood risk management and flood forecasting...

Measuring habitat suitability is important in conservation and in wildlife management. Measuring the abundance or presence-absence of a species in various habitats is not sufficient to measure habitat suitability because these metrics can be poor predictors of population success. Therefore, having some measure of population success is essential in assessing habitat suitability, but estimating p...

The potential clinical utility of engineered muscle is currently restricted by limited in vitro capacity of expanded muscle precursor cells to fuse and form mature myofibers. The purpose of this study was to use isotropic skeletal muscle sheets to explore the impact of (1) fibroblast coculture and (2) fibroblast-conditioned media (fCM) on in vitro myogenesis. Muscle sheets were prepared by seed...

In order to model multi-dimensions and multi-granularities oriented complex systems, this paper firstly proposes a kind of multi-relational Fuzzy Cognitive Map (FCM) to simulate the multi-relational system and its auto construct algorithm integrating Nonlinear Hebbian Learning (NHL) and Real Code Genetic Algorithm (RCGA). The multi-relational FCM fits to model the complex system with multi-dime...

BACKGROUND Iron deficiency is common in patients with heart failure (HF) and is associated with reduced exercise capacity and poor outcomes. Whether correction of iron deficiency with (intravenous) ferric carboxymaltose (FCM) affects peak oxygen consumption [peak VO2], an objective measure of exercise intolerance in HF, has not been examined. METHODS We studied patients with systolic HF (left...

Flow cytometry (FCM) was adapted to measure ploidy values in megakaryocytes isolated from normal guinea pigs and African green monkeys. The FCM approach was validated by microscopic identification of electronically sorted SN and higher ploidy cells and by comparisons with Feulgen microdensitometry on the same samples. Sorted 8N populations contained only megakaryocytes and were completely free ...

The purpose of this study is to apply fuzzy theory on health care. To achieve this goal, Beck Depression Inventory (BDI)-II was adopted as the instrument and outpatients of a psychiatric clinic were recruited as samples and undergraduates as non-clinical sample as well. To elicit the membership degree, we asked the subjects are free to choose more than one alternative for each item listed in BD...