نتایج جستجو برای: favism
تعداد نتایج: 143 فیلتر نتایج به سال:
Background: The purpose of this study was to determine the prevalence of G6PD deficiency in infants with jaundice in Khalij-Fars Hospital of Bandar Abbas in 2015. Methods: In this descriptive-analytic cross-sectional study, which is done in 2015 in Khalij-Fars Hospital of Bandar-Abbas, 226 infants with jaundice were entered. Admission age, hospitalization time, gender, age of birth, birth weig...
Glucose 6-phoshphate dehydrogenase is X-chromosome linked that expressed in all tissues. This is the first enzyme of pentose phosphate pathway were 5-carbon sugar Ribose and NADPH were synthesized by coupled oxidation /reduction reactions and this enzyme is a highly polymorphic enzyme in humans. G6PD deficiency are shown to be the cause of haemolytic effect of Fava beans and primaquine. It soon...
Background: Glucose-6 phosphate dehydrogenase (G6PD) deficiency is the most common inherited enzyme deficiency of red blood cells involving the enzyme pathway of hexose monophosphate. This study was conducted to examine the effect of vitamin E and folic acid on the improvement of acute hemolysis caused by the G6PD deficiency in patients referred to 17 Shahrivar Hospital, Rasht. Materials and M...
Glucose-6-Phosphate Dehydrogenase (G6PD) is a cytosolic enzyme which its main function is to produce NADPH in the red blood cells by controlling the step from Glucose-6-Phosphate to 6-Phospho gluconate in the pentose phosphate pathway. G6PD deficiency is the most common X-chromosome linked hereditary enzymopathy in the world, that result in reduced enzyme activity and more than 125 different mu...
Abstract Background About 7.5% of the world population carries one or two deficient copy of glucose-6-phosphate dehydrogenase (G6PD) genes. According to WHO, its prevalence in Iran is 10 to 14.9%. This study aimed on determination of frequency of G6PD deficiency in neonates with jaundice who were hospitalized during 6 months (September 2008 to February 2009) in the city of Yazd, Iran. Materi...
By A. SZEINBERG, CH. SHEBA AND A. ADAM W E EMBARKED ON THE STUDY of hematologic differences between Ashkenazic and non-Ashkenazic Jews#{176}when it was certain that only the latter were victims of hemolysis due to known (Vicia faba, sulpha drugs) or unknown (bacterial, viral?) noxious agents. We assumed the existence of a familial inherited trait of the red blood corpuscle, in addition to which...
Selective Occurrence of Glutathione Instability in Red Blood Corpuscles of the Various Jewish Tribes
By A. SZEINBERG, CH. SHEBA AND A. ADAM W E EMBARKED ON THE STUDY of hematologic differences between Ashkenazic and non-Ashkenazic Jews#{176}when it was certain that only the latter were victims of hemolysis due to known (Vicia faba, sulpha drugs) or unknown (bacterial, viral?) noxious agents. We assumed the existence of a familial inherited trait of the red blood corpuscle, in addition to which...
Dr. A.K. Al-Ali, College of Medicine and Medical Sciences (43), King Faisal University, P.O. Box 2114, Dammam 31451 (Saudi Arabia) It has been reported that sickle cell anemia patients have elevated serum levels of uric acid [1, 2]. This has been ascribed to altered renal function or increased bone marrow activity [3, 4]. The majority of investigations have been carried out on subjects of Afric...
Glucose-6-phosphate dehydrogenase (G6PD) deficiency is a frequent X-chromosome-linked enzyme abnormality. G6PD is the first key enzyme in the pentose phosphate metabolic pathway and is involved in the generation of NADPH, which is indispensable for biosynthesis of reduced glutathione (GSH). GSH prevents hemoglobin denaturation, preserves the integrity of red blood cell (RBC) membrane sulfhy...
Background: Sodium bicarbonate serum therapy is used for compensation bicarbonate lost and increasing blood pH in metabolic acidosis caused by severe anemia in patient with glucose-6-phosphate dehydrogenase (G6PD) deficiency. The aim of present study was comparison the effect of serum therapy using two different serums (serum with bicarbonate and without bicarbonate) on some renal and hematolo...
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