A Psicoterapia Analítica Funcional (FAP) apresenta características que dificultam e outras facilitam o trabalho com clientes não pertencem à mesma cultura terapeuta. Após uma breve consideração de algumas tendências na literatura a respeito da psicoterapia culturalmente sensível responsiva, FAP são discutidas aptas favorecer atendimento competente. São oferecidas sugestões sobre como otimizar e...

Introduction Malignant pleural mesothelioma (MPM) is an incurable malignant disease that results mostly from chronic exposition to asbestos. Fibroblast activation protein (FAP) is predominantly expressed on the surface of reactive tumor-associated fibroblasts and on particular cancer types. Therefore, FAP is an attractive target for adoptive T cell therapy. T cells can be re-directed by gene tr...

We describe the generation and characterization of a fusion protein consisting of a humanized anti-fibroblast-activating protein (anti-FAP) Ab and human TNF replacing the IgG1 CH2/CH3 Fc domain. The construct was generated by recombinant DNA technology and preserved its IgG1-derived dimeric structure with the TNF molecule linked as a dimer. Expression in CHO cells was optimized in serum-free me...

Fibroblast activation protein (FAP), as described so far, is a type II cell surface serine protease expressed by fibroblastic cells in areas of active tissue remodelling such as tumour stroma or healing wounds. We investigated the expression of FAP by fibroblast-like synoviocytes (FLSs) and compared the synovial expression pattern in rheumatoid arthritis (RA) and osteoarthritis (OA) patients. S...

La Psicoterapia Analítica Funcional (FAP) es una terapia contextual. Realiza un análisis funcional de la conducta del cliente dentro sesión clínica, aplicando contingencias reforzamiento natural y el moldeamiento, establece equivalencia entre contexto clínico vida diaria cliente. A pesar los númerosos estudios que demuestran su eficacia para tratamiento trastornos psicológicos muy diversa índol...

Attachment and ingestion of Mycobacterium avium subsp. paratuberculosis by two epithelial cell lines were enhanced by soluble fibronectin (FN). Peptide blocking of the FN attachment protein (FAP-P) inhibited the internalization of M. avium subsp. paratuberculosis. Disruption of FAP-P expression significantly reduced attachment and ingestion of M. avium subsp. paratuberculosis by T-24 and Caco-2...

Papillary thyroid carcinoma (PTC) associated with familial adenomatous polyposis (FAP) is rare. It is usually associated with the cribriform-morular variant of PTC, with unusual patterns on detailed histology examination. This variant is known to have a good prognosis. Papillary thyroid carcinoma associated with FAP commonly occurs in females in their 30s and rarely in the elderly. We report a ...