Genetic association studies have identified more than a dozen genes associated with risk of pancreatic cancer. Given this genetic heterogeneity, family history can be useful for identifying individuals at high risk for this disease. The goal of this analysis was to evaluate associations of family history of diabetes and family history of pancreatic cancer with risk of pancreatic cancer. PACIFIC...

Elevated proinsulin and proinsulin/insulin ratios are features of abnormal beta-cell function in type 2 diabetes. The participation of genetic factors is disputed. The authors wished to investigate relations between family history of diabetes on one hand and proinsulin as well as proinsulin/immunoreactive insulin ratios on the other. A large, population-based sample of Swedish men aged 35-54 ye...

A family history of diabetes determines poorer glycaemic control and younger age of diabetes onset in immigrants from the Middle East compared with native Swedes. General rights Copyright and moral rights for the publications made accessible in the public portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abi...

BACKGROUND The aim of this study was assessment of predictive factors of diabetic retinopathy. METHODS A cross-sectional study was designed by recruiting 1228 type 2 diabetic patients from a diabetes referral clinic over a six-month period (from July to December, 2012). Diabetes risk factors, complications, laboratory results have been recorded. RESULTS Of the 1228 diabetic patients (54% wo...

OBJECTIVE To assess the association between diabetes family history and infant feeding patterns. DESIGN Data on breast-feeding duration and age at first introduction of cow's milk and gluten-containing cereals were collected in 3-month intervals during the first 24 months of life. SETTING Data from the multicentre TEDDY (The Environmental Determinants of Diabetes in the Young) study, includ...

background: obesity is one of the known risk factors of diabetes. nowadays in parallel with industrialization of societies, changes in lifestyle and diet habits and also decreased physical activity, the prevalence of obesity is increasing. the objective of this study is to evaluate the effect of change in body weight on blood glucose disorders rate after 3 years of tehran lipid and glucose stud...

OBJECTIVE The purpose of this article was to examine metabolic risk factors for type 2 diabetes in children and adolescents as a function of maternal versus paternal family history of type 2 diabetes and to examine whether differences in these risk factors emerge during adolescent growth. RESEARCH DESIGN AND METHODS A total of 247 overweight Latino children (baseline age = 11.1 +/- 1.7 years)...

background: a case-control study was carried out to investigate the roles of prior allergies and family history of cancers and their interaction in the etiology of adult leukemia. methods: prior allergies status and family history of cancers in first-degree relatives were compared between 131 incident leukemia cases and 206 hospital-based controls. odds ratios (or) were estimated using an uncon...