Background: Disorganization of tonotopy in the auditory cortex has been described in schizophrenia. Subjects with schizophrenia show little to no spatial organization of responses to different tone frequencies in the auditory cortex. Previous studies have called into question the use of MEG and the M100 response to assess tonotopy. This study seeks to replicate prior results of tonotopic disorg...

Foster care offers children a safe family environment and is effective in buffering the negative effects of early adversity. Specifically, foster has been found to facilitate secure attachment parents. However, there are limited data on development entering after first year life. In this study, we examined behaviour representations as well symptoms reactive disorder (RAD) disinhibited social en...

Robert J. Sampson and W. Byron Groves (1989) analyzed data from 238 British neighborhoods to test the mediating effect of indicators of social disorganization. Basing their work on that of Clifford R. Shaw and Henry D. McKay (1942), these researchers created indicators such as friendship networks, organizational participation, and the control of street-corner teenaged peer groups, and developed...

In 1990, M. Main and J. Solomon introduced the procedures for coding a new "disorganized" infant attachment classification for the Ainsworth Strange Situation procedure (M.D.S. Ainsworth, M. Blehar, E. Waters, & S. Wall, 1978). This classification has received a high degree of interest, both from researchers and from child welfare and clinical practitioners. Disorganized attachment has primaril...

Hurricane Katrina brought to the surface serious questions about the capacity of the public health system to respond to community-wide disaster. The storm and its aftermath severed developmentally protective family and community ties; thus its consequences are expected to be particularly acute for vulnerable adolescents. Research confirms that teens are at risk for a range of negative outcomes ...

BACKGROUND Autism spectrum disorders (ASD) are etiologically heterogeneous and complex. Functional genomics work has begun to identify a diverse array of dysregulated transcriptomic programs (e.g., synaptic, immune, cell cycle, DNA damage, WNT signaling, cortical patterning and differentiation) potentially involved in ASD brain abnormalities during childhood and adulthood. However, it remains u...

Cell death occurs in all eukaryotes, but it is still not known whether some core steps of the cell death process are conserved. We investigated this using the protist Dictyostelium. The dissection of events in Dictyostelium vacuolar developmental cell death was facilitated by the sequential requirement for two distinct exogenous signals. An initial exogenous signal (starvation and cAMP) recruit...

Nineteen healthy parents of long-term schizophrenia outpatients were assessed for levels of expressed emotion (EE) and for characteristics of communication style which are putative markers of vulnerability to schizophrenia. We administered measures of communication deviance, linguistic reference performance, global disorganization, and positive formal thought disorder. Parents high in EE showed...

This study examined the relationships among disorganization, self-efficacy, and coping as predictors of depressive symptoms in women. Chronic disorganization (CD) is a particularly interesting area to examine because of its wide-spread impact on people (which can be seen by the existing number of professional organizers, their even larger number of clients, and mediarelated stories covering thi...