Introduction Familial Mediterranean Fever (FMF) is the most common periodic fever syndrome, characterized by recurrent fever and serositis attacks. Colchicine is the treatment of choice. Colchicine is given in two or three divided doses due to its side effects. It has been stated that colchicine unresponsive patients are in fact non-compliers because there is an inverse relationship between dai...

OBJECTIVE The purpose of the present study was to analyse the evolution of the Spanish population's global and regional adherence to the Mediterranean diet (MD) since 1987. DESIGN A cross-sectional study was conducted analysing food consumption from the Spanish Household Consumption Surveys administered by the Spanish Ministry of Agriculture, Fisheries and Food. SETTING The Mediterranean Ad...

Postoperative respiratory distress and pulmonary edema can be seen after a wide variety of serious clinical situations, or rare diseases such as familial Mediterranean fever (FMF). FMF is a multisystemic disorder characterized by recurrent bouts of fever and pain due to inflammation of the peritoneum, synovia, or pleura. We report a case with history of FMF who developed postoperative respirato...

Mediterranean temporary ponds (MTPs) comprise an endangered habitat with several endemic species that can be found in many countries, mainly in the Mediterranean region but are disappearing at a high rate. For designing optimal conservation and management strategies for the particular ecosystems, appropriate characterization and classification of these ponds is necessary based on the different ...

Neutrophilic Lobular Panniculitis as an Expression of aWidened Spectrumof Familial Mediterranean Fever Familial Mediterranean fever (FMF) is considered to be an autosomal recessive disease, though it is controversial.1-3 The marenostrin-encoding fever gene (MEFV) is responsible for FMF. The most frequent mutation is M694V, which represents a genetic risk factor for development of amyloidosis1 a...

Familial Mediterranean fever (FMF) is an inherited autosomal recessive disorder, ethnically restricted and commonly found among populations surrounding the Mediterranean Sea. FMF is the most prevalent autoinflammatory disease; is characterized by recurrent, self-limited episodes of fever with serositis; and is caused by Mediterranean fever gene (MEFV) mutations on chromosome 16. We describe a c...

BACKGROUND/AIMS Three missense mutations clustered on the carboxyl-terminal portion of the MEFV gene (M680I, M694V, and V726A) have been observed in over 80% of affected alleles in several ethnic groups of familial Mediterranean fever patients. Several immunologic abnormalities were found both in cellular and humoral components in Mediterranean fever patients. Those observations have pointed th...

Familial periodic fever syndromes, otherwise known as hereditary autoinflammatory syndromes, are inherited disorders characterized by recurrent episodes of fever and inflammation. The general hypothesis is that the innate immune response in these patients is wrongly tuned, being either too sensitive to very minor stimuli or turned off too late. The genetic background of the major familial perio...

background: familial mediterranean fever (fmf) has episodic or subclinical inflammation that may lead to a decrease in bone mineral density (bmd). the objective of this study was to assess bmd in egyptian children with fmf on genetic basis. methods: a cross sectional study included 45 fmf patients and 25 control children of both sexes in the age range between 3-16 years old. the patients were r...

familial mediterranean fever (fmf) is a relatively rare disorder, characterized by recurrent self-limited attacks of fever and polyserositis. diagnosis is made by clinical features, gene identification on chromosome 16 and clinical response to specific treatment. different types of vasculitis have been reported in fmf. henoch-schönlein purpura (hsp) is one of them, usually with a benign clinica...