Numerous studies have described altered patterns of craniofacial form in the unaffected relatives of individuals with nonsyndromic clefts. Unfortunately, results from such studies have been highly variable and have failed to provide a reliable method for differentiating "at-risk" relatives from controls. In the present study, we compared craniofacial shape between a sample of unaffected relativ...

OBJECTIVES To evaluate the sensitivity and specificity of ultrasound for detecting prenatal facial clefts in low-risk and high-risk populations. METHODS This study prospectively followed up a non-selected population, namely all pregnant women who underwent routine second-trimester prenatal ultrasound screening in the Utrecht region during the 2-year period from January 2007 to December 2008. ...

The occurrence of dental abnormalities affecting both the primary and permanent dentition in children with oral clefts has been well documented.1-5 These abnormalities can be in the number, morphology, or eruption pattern of the teeth and are more frequent in children with clefts than in children without clefts.1 Specifically, both supernumerary and fused teeth have been shown to occur with gre...

Background: Clefts of the lip, palate, or both are most prevalent form facial congenital abnormality among neonates. In improving health neonates born with craniofacial deformities, neonatal nurses played a crucial role in educating parents and spreading awareness about disease. Aim: to assess mothers' knowledge practices regarding cleft palate infant feeding patterns. The study was descriptive...