This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/ by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Natural killer (NK)-or T-cell lymphomas of the gastrointes-tinal (GI) tract are uncommon, a...

Background: Primary lymphomas of the heart are very rare, especially primary cardiac extranodal natural killer/T-cell Lymphoma. Primary cardiac natural killer/T-cell lymphoma has diversified symptoms and the diagnosis is difficult. Case presentation: We have reported a 35 year old man with palpitation, fever and increasing dyspnea. Transthoracic echocardiography was done and showed a large piec...

Extranodal NK/T cell lymphoma (ENKTL), nasal type is a rare, aggressive disease affecting the midfacial and nasopalatal region in the head. The pathogenesis of the disease is unknown, but the disease has been linked to Epstein Barr virus (EBV) infection. Early diagnosis of the disease is the best way to increase the prognosis and quality of life in the patients. However, it is still a challenge...

The new World Health Organization / European Organization for Research and Treatment of Cancer (WHO-EORTC) consensus classification for cutaneous lympho-mas recognizes two main groups of CD56 + lymphomas: extranodal natural killer (NK)/T-cell lymphoma nasal type, and CD56+ haematodermic neoplasm (formerly known as blastic NK cell lymphoma (1). NK/T-cell lymphoma nasal type is the most common ly...

A case of sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman syndrome) in a 42-year-old man is described. The disease involved the respiratory tract and skeletal apparatus, led to considerable general impairment and was unusually responsive to glucocorticoids. Molecular and immunophenotype analysis seem to confirm the reactive nature of a disorder that shows profound T-cell immunod...

Extranodal natural killer/T-cell lymphoma (ENKTL), nasal type, is a distinct entity of non-Hodgkin lymphoma with interesting unique biologic and clinicopathologic features. The tumor is characterized by ethnic preponderance, a consistent association with Epstein-Barr virus (EBV) infection, peculiar histopathologic findings, and a predilection to affect primarily the upper aerodigestive tract, i...