Recent studies have demonstrated a strong association between carcinogenesis and re-activation of telomerase in various human tumors. In the present study, we have analyzed the telomerase activity in 105 oral mucosal samples, including normal mucosa and premalignant and malignant lesions, by using the telomeric repeat amplification protocol assay. The telomerase activity was detected in normal ...

PURPOSE The objective of this study was to evaluate the diagnostic concordance characteristics of oral cavity lesions by comparing the clinical diagnosis of the lesions with the histopathologic diagnosis. MATERIAL AND METHOD A retrospective analysis was conducted on the patients, who were admitted with oral cavity pathology and underwent biopsy procedure between 2007 and 2011. The oral cavity...

BACKGROUND Dysgenetic polycystic salivary gland disease is a rare pathology. No case of minor salivary gland involvement has been reported in the literature. METHODS A female patient presented with bilateral tumors of the parotid glands, bilateral submandibular gland enlargement, and multiple cystic lesions of the oral mucosa. MRI of the neck was performed along with fine-needle aspiration (F...

A clinicopathological study was made on 45 autopsy cases of brain tumors treated with radiotherapy. Morphological changes after radiotherapy were classified into six categories : 1) tumor disappearance, 2) small residual tumor, 3) extensive tumor necrosis, 4) proliferative tumor growth, 5) mixed glioblastoma and fibrosarcoma, and 6) no remarkable change. When the tumors are primarily radiosensi...

The pivotal reason for morbidity and mortality of any type of cancer is due to metastasis that occurs as a result of adaptation of genetically unstable cancer cells, in an ectopic conducive environment. Oral metastasis in spite of being unusual or rare represents around 25% of the first signs of metastatic spread. Literature says there are more number of cases of jaw bone metastasis reported th...

Objectives The aim of the present study was to document the frequency and clinicopathologic features of intra-osseous jaw lesions in an Iranian pediatric population over a 20-year period. Methods Data were obtained from the archives of the Oral Pathology Department, Shahid Beheshti University of Medical Sciences, Tehran, Iran. The lesions were classified into four groups: (A) odontogenic cysts...

▼ BENIGN “VIRUS-INDUCED” TUMORS (ORAL SQUAMOUS PAPILLOMAS AND WARTS) ▼ SYNDROMES WITH BENIGN ORAL NEOPLASTIC OR HAMARTOMATOUS COMPONENTS Von Recklinghausen’s Neurofibromatosis Gardner’s Syndrome Peutz-Jeghers Syndrome Nevoid Basal Cell Carcinoma Syndrome Multiple Endocrine Neoplasia Type III (Multiple Mucosal Neuroma Syndrome) Tuberous Sclerosis Acanthosis Nigricans Albright’s Syndrome Paget’s ...