Diabetic ulcers on the lower extremities present a difficult treatment problem, and some ulcers respond poorly to conventional topical and cast treatment. The purpose of this study was to assess the effect of cultured allogeneic keratinocyte epithelium and fibroblast-gelatin sponge on the healing of chronic, refractory diabetic leg and foot ulcers. Non-diabetic chronic leg ulcers were treated f...

OBJECTIVE We tested the hypothesis that LED phototherapy with combined 660-nm and 890-nm light will promote healing of venous ulcers that failed to respond to other forms of treatment. BACKGROUND DATA A variety of dressings, growth factors, and adjunct therapies are used to treat venous ulcers, but none seems to yield satisfactory results. MATERIALS AND METHODS We used a randomized placebo-...

BACKGROUND Because the demand for government-subsidized nursing homes in Hong Kong outstrips the supply, the number of for-profit private nursing homes has been increasing rapidly. However, the standard of care in such homes is always criticized. Pressure ulcers are a major long-term care issue that is closely associated with the quality of care delivered in nursing home settings. The aim of th...

UNLABELLED Amniotic membrane (AM) can promote proper epithelialization with suppression of excessive fibrosis by creating a supportive milieu for regeneration of chronic ulcer bed. OBJECTIVE The objective of this study is to investigate whether AM scaffold can modulate the healing of a wound by promoting tissue reconstruction rather than promoting scar tissue formation. SUBJECTS AND METHODS...

The effect of different extracts of leaves and fruits of Moringa oleifera Lam. (Moringaceae) on gastric and duodenal ulcers was evaluated by using different gastric ulcer models and cysteamine-induced duodenal ulcer method. The leaf extracts (500mg=kg, p.o.) of Moringa oleifera showed gastric ulcer healing effect in acetic acid–induced chronic gastric ulcers. The acetone extract and methanol ex...

Digital ulcers are a well-known problem in patients with systemic sclerosis. Lower extremity ulcers are less prevalent but are also a challenging and underestimated complication of the disease causing important pain and morbidity. Bosentan, an oral dual endothelin receptor antagonist, has been shown to be effective in preventing digital ulcers in patients with systemic sclerosis. A few recent o...

Data from the National Nursing Home Survey, 2004. In 2004, about 159,000 current U.S. nursing home residents (11%) had pressure ulcers. Stage 2 pressure ulcers were the most common. Residents aged 64 years and under were more likely than older residents to have pressure ulcers. Residents of nursing homes for a year or less were more likely to have pressure ulcers than those with longer stays. O...