Pompe's disease (acid maltase deficiency) classically affects infants and children, with a few sporadic cases occurring in adults. An adult patient initially have progressive muscular weakness, exertional dyspnea, diaphragmatic paralysis, and objective evidence of restrictive respiratory disease. Muscle biopsy established the diagnosis of acid maltase deficiency. The patient's brother had died ...

conclusions the authors emphasize on the rarity of this pathology among children, its clinical polymorphism, the necessity of a rapid diagnosis, and an appropriate treatment to avoid complications and recurrence of the tumor. introduction right atrial myxoma is a rare disease among children and its clinical presentation is not specific. case presentation we reported a four-year-old girl with ex...

This case involves a 36 year old non-smoker who worked in a factory producing food flavourings for potato crisps. He developed exertional breathlessness associated with fixed airway obstruction shortly after an uncharacteristically high exposure to the food flavouring chemical diacetyl. Unfortunately, even though he was removed from further exposure to this agent, his symptoms and spirometry di...

BACKGROUND This study evaluated the effects of aclidinium bromide, a long-acting muscarinic antagonist indicated for maintenance treatment of chronic obstructive pulmonary disease (COPD), on exercise endurance, dyspnea, lung hyperinflation, and physical activity. METHODS In this randomized, double-blind, crossover study, patients with stable COPD and moderate-to-severe airflow limitation rece...

3 years ago, 38-year-old male, with no relevant personal pathological history, began to present exertional dyspnea, gastroesophageal reflux, retrosternal pyrosis, dyspepsia and postprandial abdominal distension after a traffic accident. A study protocol was initiated, where cabinet studies documented elevation of the left hemidiaphragm documented. minimally invasive approach performed finding a...

A 24-year-old woman presented with a 3-week history of exertional dyspnea and dry cough. Her medical history was remarkable for rheumatoid arthritis (RA). She had no exacerbation of joint symptoms during the prior 2 years. She denied fever or other constitutional symptoms. She took ibuprofen occasionally but no other antirheumatic medications. She was a lifelong nonsmoker. Her review of systems...

Primary cardiac tumors are a rare entity. The presence of a mass in the left atrium suggests myxoma as a first differential diagnosis. Here we present a rare case of a woman with exertional dyspnea with a large tumor in the left atrium. The patient was extensively studied with echocardiography, cardiac MRI, coronary angiography and computed tomography. Extracardiac neoplastic involvement was ru...