To the Editor: Nylen and colleagues reported that physical fitness, as represented by exercise capacity, reduces the risk of mortality in people with diabetes mellitus regardless of age. I compliment the authors on their excellent study. I would also like to mention that data were reported from a study of 609 people with diabetes mellitus with a mean age of 70 with no history of coronary artery...

PURPOSE To compare the contributions of fitness level and physical activity patterns to all-cause mortality. METHODS Of 6213 men referred for exercise testing between 1987 and 2000, 842 underwent an assessment of adulthood activity patterns. The predictive power of exercise capacity and activity patterns, along with clinical and exercise test data, were assessed for all-cause mortality during...

Mice are commonly used to examine the mechanisms by which exercise improves cardiometabolic health; however, exercise compliance and adaptations are often strain-dependent or are variable due to inconsistency in exercise training protocols. In this study, we examined nocturnal/diurnal behavior, treadmill exercise compliance, and systemic as well as cardiac-specific exercise adaptations in two c...

OBJECTIVE To evaluate the effect of lung resection on lung function and exercise capacity values, including diffusion capacity of the lung for carbon monoxide (Dlco), during exercise, and to determine whether postoperative lung function, including exercise capacity and Dlco during exercise, could be predicted from preoperative lung function and the number of functional segments resected. DESI...

Little is known about the effects of sequential combination therapy on exercise capacity in pulmonary arterial hypertension (PAH). We monitored exercise capacity by cardiopulmonary exercise testing (CPX) and observed the benefit of using a peak oxygen uptake (VO2) cut-off of 15 mL/min/kg to guide combination therapy. The patients underwent CPX at baseline and after 3, 6, and 12 months. In patie...