conclusions although the frequency of hbsag seropositivity in the present study was close to that observed in the overall iranian population, the seroprevalence of anti-hbc was higher, possibly due to the exposure of the elderly to more risk factors. the risk factors were similar. these included a history of blood transfusions, cupping, hospital admission, endoscopy, or familial hbv/hcv infecti...

background and objectives:  the molecular genetic of the human herpes virus 8 (hhv8) has now been characterized the pathogenesis of kaposi sarcoma (ks). this study attempted to determine the rate of hhu-8 infection in ks in an iraniann cross sectional study. method & material: in this cross-sectional study, we used paraffin-embedded specimens of 54 clinically well-characterized kaposi sarco...

background & objective: the current approaches to reduce the risk of colorectal carcinoma are through the detection and removal of the precursor lesion” adenomatous polyps”. the study was conducted to evaluate the immunohistochemical expression of p53 and bcl2 in colorectal adenomas and carcinomas. patients and methods: a total of 86 cases, 33 colorectal adenomas, 33 colorectal adenocarcin...

results our study showed that there were no statistically significant differences in the allele and genotype frequencies of -1661 a/g snp between patients with sle and healthy controls (p > 0.05). conclusions in conclusion, we found no association between snp-1661 a/g of the ctla-4 promoter region and susceptibility to sle in our population. objectives to evaluate the potential influences of co...

abstract background ulcerative colitis (uc) is characterized by recurrent episodes of inflammation limited to the mucosal layer of the colon. calprotectin is a zinc and calcium binding protein derived from neutrophils and monocytes. it is easily detectable in tissue samples, body fluids, and stools, which makes it a potentially valuable marker of inflammation. the aim of the current study is to...

the genome of hb v virus of serotype ayw cloned in pbr322 and expression shuttle vector p yes2 were used for construction of the hbsag chimeric genes and their expression in saccharomyces cerevisiae. two recombinant plasmids were constructed. one of them contained the coding sequences for the major polypeptide of surface antigen. another construct carried the major polypeptide with the pre-s2 a...

to prepare hemagglutination inhibition (hi) antigen the egg drop syndrome virus (edsv) was propagated in 10-day-old embryonated duck eggs. the virus antigen was inactivated with two methods including heating (65°c) and adding 0.5% formaldehyde by considering low destroying effect on hemagglutination (ha) and hi titers. the edsv hi titers of 310 sera and 100 yolks obtained from 23 chicken farms ...

the measurement of antibody responses of animals exposed to bvdv either through a natural exposure or an immunization protocol is still a standard procedure. for bvdv, the test formats have been largely limited to elisa which is a valuable diagnostic test to measure the level of bvdv specific antibodies as well as antigen in blood samples. in the present study, 120 blood samples were collected ...

background: hydatidosis is one of the most important helminthic diseases causing serious health and economic problems in many countries including iran. currently available diagnostic approaches for diagnosis of cystic echinococcosis (ce) are not satisfactory since they have not achieved a reasonable validity in diagnosis of ce. this study aimed to assess the perform¬ances of western blotting (w...

Background and Aims: Influenza is an acute respiratory illness that is caused by a virus belonging to Orthomyxoviridae family. This virus spreads rapidly every year in cold season and leads to morbidities and mortalities especially in adults and children, which causes billions of dollars of economic losses. Accordingly, development of a rapid, sensitive and inexpensive laboratory diagnosis base...