نتایج جستجو برای: euroimmun
تعداد نتایج: 140 فیلتر نتایج به سال:
Background Patients on immunomodulatory treatments mount an attenuated immune response following mRNA COVID-19 vaccination, yet long-term studies of vaccine-induced anti-SARS-CoV-2 antibody (Ab) kinetics are missing. Objectives In this prospective observational study, we mapped the humoral to vaccines up 24 weeks post full vaccination in patients with inflammatory rheumatic diseases (IRDs). We ...
Since its appearance in Wuhan, China, late December 2019, the novel coronavirus SARS-CoV-2 has rapidly spread, causing over 1.2 million deaths worldwide as of early November 2020.1 Currently, no targeted therapy is available for associated disease COVID-19, but several options are being investigated, including COVID-19 convalescent plasma (CCP). Its use relies on principle passive immunity. One...
While nucleic acid amplification tests remain the gold-standard for diagnosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections, immunological methods can also be used to detect viral antigens or specific antibodies.1-9 Several rapid diagnostic employing antigen detection (Ag-RDTs) are now commercially available. However, there remains limited evidence on utility Ag-RDT...
A 20-year-old woman developed anti–NMDA receptor (NMDAR) encephalitis with psychosis, dysphagia, hemiparesis, generalized dystonia, cortical blindness, and status epilepticus. IgG NMDAR antibodies were present in serum and CSF (figure). She was successfully treated with IV immunoglobulin (IVIg), plasmapheresis, and carbamazepine. She relapsed 1.5 years later and was treated regularly with IVIg ...
Medical care is entering into a new phase of “personalized” medical care in which diagnosis and management are tailored to the specific aspects of individual patients. This approach is often guided by the results of sophisticated biomarkers of disease, prognosis, or treatment responsiveness. In this issue of CJASN, Bech and coworkers from the Radboud University Medical Center (Nijmegen, The Net...
COVID-19 cases are very high across Europe. Current measures not reducing virus spread sufficiently, and new SARS-CoV-2 variants emerging. The B.1.1.7 B1.351 variants, first identified in the UK South Africa, respectively, have to many European countries.1European Centre for Disease Prevention ControlRapid increase of a variant with multiple spike protein mutations observed United Kingdom. Dec ...
•New dopa-responsive phenotype expands the spectrum of GlyR antibody-associated PERM syndrome.•Appendicular rigidity with axial hypotonia and oculomotor abnormalities suggested hypodopaminergic tone.•Downstream effects antibody may interfere dopamine network. Progressive encephalomyelitis myoclonus (PERM) syndrome is a rare autoimmune encephalitis, often associated glutamic acid decarboxylase (...
Objective: To describe the phenotypes, treatment response, and outcome of IgLON5 autoimmunity. Methods: Archived serum and CSF specimens from 367 patients known to harbor unclassified antibodies which stained neural synapses diffusely (mimicking amphiphysin-IgG) were reevaluated by indirect immunofluorescence assay (IFA) using a composite of mouse tissues and recombinant IgLON5-transfected cell...
Objective: To report the distinctive clinical features of cryptogenic new-onset refractory status epilepticus (C-NORSE) and the C-NORSE score based on initial clinical assessments. Methods: A retrospective studywas conducted for 136 patients with clinically suspected autoimmune encephalitis who underwent testing for autoantibodies to neuronal surface antigens between January 1, 2007, and August...
s of the 19th Annual Congress of the SBRA, Búzios, RJ, 05-08 August 2015 tes fertilization among women performing IVF/ICSI. Methods: A case-control study was performed. The population comprised women with diagnosis of endometriosis, with or without endometrioma cysts, presenting to IVF/ ICSI procedures. Risk (Odds Ratio – OR) of endometrioma to generate fragmented embryos (B/C/D) or to affect f...
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