OBJECTIVE To examine tobacco industry marketing of menthol cigarettes and to determine what the tobacco industry knew about consumer perceptions of menthol. METHODS A snowball sampling design was used to systematically search the Legacy Tobacco Documents Library (LTDL) (http://legacy.library.ucsf.edu) between 28 February and 27 April 2010. Of the approximately 11 million documents available i...

BACKGROUND African Americans have higher tobacco-related morbidity and mortality and are more likely to smoke menthol cigarettes than their white counterparts. This study examined differences between African American menthol and non-menthol smokers in smoking characteristics and cessation. METHODS The study sample consisted of 600 African American smokers enrolled in a clinical trial that ass...

Menthol, the cooling natural product of peppermint, is widely used in medicinal preparations for the relief of acute and inflammatory pain in sports injuries, arthritis, and other painful conditions. Menthol induces the sensation of cooling by activating TRPM8, an ion channel in cold-sensitive peripheral sensory neurons. Recent studies identified additional targets of menthol, including the irr...

humic acid as an organic substance can bound heavy metals. it is a best way of decreasing the hazardous effect of heavy metals on plants and thereby on humans. a factorial experiment was conducted in a completely randomized design of seven replications. the treatments consisted of three cadmium levels (0, 2 and 4 mgl-1), and three humic acid levels (0, 100, 1000 mgl-1) added to nutrient solutio...

In a controlled prospective double blind trial patients with cholesterol gall bladder stones are treated with ursodeoxy-cholic acid (group A: UDCA 11.1 mg/kg per day; n = 16) and Ursomenth respectively (group B: a mixture of UDCA/menthol: 4.75 mg/kg per day each; n = 17). With same stone number and size (10-12 mm) there is a complete dissolution rate in group A of 38%, and of 53% in group B wit...

The main purpose of the present study is to predict optimal values ultrasound-extraction conditions by employing response surface method based on Box–Behnken design from Moringa oleifera leaves. impact three independent variables, namely extraction time (5,15, and 25 min), solid solvent ratio (60%, 70%, 80%), ultrasonic amplitude (20%, 60%, 100%) yield total phenolic/flavonoid content were stud...

The purpose of this study was to evaluate the histopathological effect of eugenol and bis-eugenol on oral mucous membranes at the tissue organ level. Oral mucous membranes of mice were applied with three reagents, eugenol, bis-eugenol, and acetone (as the control). The control group showed a normal architecture. The eugenol group showed severe hyperkeratosis, parakeratosis, cellular edema, patc...

Formaldehyde and phenol biodegradation during the denitrification process was studied at lab-scale, first in anoxic batch assays and then in a continuous anoxic reactor. The biodegradation of formaldehyde (260 mgl(-1)) as single carbon source and at phenol concentrations ranging from 30 to 580 mgl(-1) was investigated in batch assays, obtaining an initial biodegradation rate around 0.5g CH(2)Og...