Rhamnus prinoides L’Herit belongs to Rhamnaceae family widely distributed in India, Eastern, Central and Southern Africa. In Ethiopia it is commonly known as Gesho (Amharic, Tigrigna Afan Oromo), Gishe (Guragegna) Geshu (Agewgna). Decoction of the leaves recommended remedy for treatment variety diseases such back pain, malaria, pneumonia, sexually transmitted disease, skin infections, wounds, b...