نتایج جستجو برای: ethinylestradiol

تعداد نتایج: 673  

Journal: :Environmental toxicology and chemistry 2009
June-Woo Park Amber R Tompsett Xiaowei Zhang John L Newsted Paul D Jones Doris W T Au Richard Kong Rudolf S S Wu John P Giesy Markus Hecker

In an earlier study, we described the development of fluorescence in situ hybridization (FISH) using confocal microscopy to localize and quantify gene expression in fish. Here, we report the results of FISH application to investigate effects of model endocrine-disrupting chemicals (EDCs), 17alpha-ethinylestradiol (EE2) and 17beta-trenbolone (TB), on expressions of EDC-responsive genes in Japane...

Journal: :American journal of physiology. Gastrointestinal and liver physiology 2007
Flavia I Carreras Guillermo L Lehmann Domenico Ferri Mariana F Tioni Giuseppe Calamita Raúl A Marinelli

Our previous work supports a role for aquaporin-8 (AQP8) water channels in rat hepatocyte bile formation mainly by facilitating the osmotically driven canalicular secretion of water. In this study, we tested whether a condition with compromised canalicular bile secretion, i.e., the estrogen-induced intrahepatic cholestasis, displays defective hepatocyte AQP8 functional expression. After 17alpha...

Journal: :Aquatic toxicology 2015
Christopher Green Jayne Brian Rakesh Kanda Martin Scholze Richard Williams Susan Jobling

Sexual disruption in wild fish has been linked to the contamination of river systems with steroid oestrogens, including the pharmaceutical 17α-ethinylestradiol, originating from domestic wastewaters. As analytical chemistry has advanced, more compounds derived from the human use of pharmaceuticals have been identified in the environment and questions have arisen as to whether these additional p...

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