All cancers tested so far display abnormal choline and ethanolamine phospholipid metabolism, which has been detected with numerous magnetic resonance spectroscopy (MRS) approaches in cells, animal models of cancer, as well as the tumors of cancer patients. Since the discovery of this metabolic hallmark of cancer, many studies have been performed to elucidate the molecular origins of deregulated...

Adenosylcobalamin (Ado-B12) is both the cofactor and inducer of ethanolamine ammonia lyase (EA-lyase), a catabolic enzyme for ethanolamine. De novo synthesis of Ado-B12 by Salmonella enterica occurs only under anaerobic conditions. Therefore, aerobic growth on ethanolamine requires import of Ado-B12 or a precursor (CN-B12 or OH-B12) that can be adenosylated internally. Several known enzymes ade...

A pleiotropic mutant of Paracoccus denitrificans, which has a severe defect that affects its anaerobic growth when either nitrate, nitrite, or nitrous oxide is used as the terminal electron acceptor and which is also unable to use ethanolamine as a carbon and energy source for aerobic growth, was isolated. This phenotype of the mutant is expressed only during growth on minimal media and can be ...

K, and V,,,,,. values for ethanolamine, 1 -aminopropan-2-01s and their phosphate derivatives, with the kinase and phospho-lyase enzymes respectively, indicated that the pathway in Pseudomonas sp. N.C.I.B. 8858 was concerned with 1-aminopropan-2-01 degradation. (L-1-Aminopropan-2-01 is a metabolite of aminoacetone, derived from L-threonine, and D-1-aminopropan-2-01 is a fragment of vitamin B12 c...

Evidence was also obtained that the dismutation of acetaldehyde was accompanied by phosphorylation of ADP, presumably via intermediary acetyl phosphate, to form ATP. During the course of these studies, Hayward (4) isolated a clostridium from a medium that contained choline as a major source of energy. This organism was found to catalyze the same over-all fermentation of choline as that of the v...

Soil-borne pathogens such as Verticillium species, invade into the roots of many herbaceous and woody hosts. The xylem environment supplies these with a continuous flow nitrogen-rich nutrition. Detailed quantitative increases in amino acids stems, petioles, leaflets young tomato plants infected Verticillium. albo-atrum causal agent wilt disease, are described this paper for first time. Results ...

Ethanolamine plasmalogen (PlsEtn), a subclass of ethanolamine glycerophospholipid (EtnGpl), has been reported to have many biological and dietary functions. In terms PlsEtn absorption, some studies that is re-esterized at the sn-2 position using lymph cannulation everted jejunal sac model. this study, we aimed better understand uptake kinetics increase its absorption. We thus compared with lyso...

BACKGROUND Vibrio fluvialis is an emerging diarrheal pathogen for which no genome is currently available. In this work, draft genomes of two closely related clinical strains PG41 and I21563 have been explored. RESULTS V. fluvialis strains PG41 and I21563 were sequenced on the Illumina HiSeq 1000 platform to obtain draft genomes of 5.3 Mbp and 4.4 Mbp respectively. Our genome data reveal the p...