نتایج جستجو برای: esophageal tumor

تعداد نتایج: 469952  

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2004
Nan Hu Michael J Flaig Hua Su Jian-Zhong Shou Mark J Roth Wen-Jun Li Chaoyu Wang Alisa M Goldstein Guang Li Michael R Emmert-Buck Philip R Taylor

PURPOSE The purpose is to characterize alterations of the annexin I gene, its mRNA, and protein expression in esophageal squamous cell carcinoma. EXPERIMENTAL DESIGN Fifty-six cases of esophageal squamous cell carcinoma were analyzed using four microsatellite markers flanking the annexin I gene (9q11-q21) to identify loss of heterozygosity. In addition, we performed (a) single-strand conforma...

2013
Charalampos G. Markakis Eleftherios D. Spartalis Emmanouil Liarmakopoulos Evangelia G. Kavoura Periklis Tomos

Introduction. Gastrointestinal stromal tumors of the esophagus are rare. Case Presentation. This is a case of a 50-year-old male patient who was referred to our department complaining of atypical chest pain. A chest computed tomographic scan and endoscopic ultrasound revealed a submucosal esophageal tumor measuring 5 cm in its largest diameter. Suspecting a leiomyoma, we performed enucleation v...

2000
M. Feith

The development of new sensitive immunohistochemical methods allows the detection of single tumor cells or cell clusters in lymph nodes staged as tumor free on routine histologic examination. The prevalence and prognostic impact of these so-called lymph node ‘micrometastases’ has been studied in a variety of different tumor types. Only limited and still somewhat conflicting data are available f...

Journal: :Cancer research 2013
Rifat Hasina Nathan Mollberg Ichiro Kawada Karun Mutreja Geetanjali Kanade Soheil Yala Mosmi Surati Ren Liu Xiuqing Li Yue Zhou Benjamin D Ferguson Vidya Nallasura Kenneth S Cohen Elizabeth Hyjek Jeffery Mueller Rajani Kanteti Essam El Hashani Dorothy Kane Yutaka Shimada Mark W Lingen Aliya N Husain Mitchell C Posner Irving Waxman Victoria M Villaflor Mark K Ferguson Lyuba Varticovski Everett E Vokes Parkash Gill Ravi Salgia

Esophageal cancer incidence is increasing and has few treatment options. In studying receptor tyrosine kinases associated with esophageal cancers, we have identified EPHB4 to be robustly overexpressed in cell lines and primary tumor tissues. In total, 94 squamous cell carcinoma, 82 adenocarcinoma, 25 dysplasia, 13 Barrett esophagus, and 25 adjacent or unrelated normal esophageal tissues were ev...

Journal: :The American journal of surgical pathology 2007
Parakrama Chandrasoma Kumari Wickramasinghe Yanling Ma Tom DeMeester

BACKGROUND Adenocarcinoma of the distal esophagus and gastric cardia are defined by the relationship of its epicenter to the gastro-esophageal junction, which is presently defined as the end of the tubular esophagus. We have recently suggested that the true gastro-esophageal junction is best defined by the proximal limit of gastric oxyntic mucosa. AIM To reclassify adenocarcinomas of this reg...

Journal: :acta medica iranica 0
mohammad sadeghi hasanabadi otorhinolaryngology research centre, imam khomeini hospital, tehran university of medical sciences, tehran, iran. mandana amiri otorhinolaryngology research centre, amiralam hospital, tehran university of medical sciences, tehran, iran. ardavan tajedini otorhinolaryngology research centre, amiralam hospital, tehran university of medical sciences, tehran, iran. alireza karimi yazdi otorhinolaryngology research centre, imam khomeini hospital, tehran university of medical sciences, tehran, iran. mona heidarali otorhinolaryngology research centre, amiralam hospital, tehran university of medical sciences, tehran, iran. amin amali otorhinolaryngology research centre, imam khomeini hospital, tehran university of medical sciences, tehran, iran.

although esophageal liposarcoma is an extremely rare tumor, liposarcoma is the most common soft tissue sarcoma in adults. liposarcoma is currently classified into the types of well-differentiated, myxoid, round cell, pleomorphic and dedifferentiated liposarcoma. up to now only a few cases of esophagus liposarcoma have been described in the world literature. we describe a myxoid type liposarcoma...

Journal: :reports of biochemistry and molecular biology 0
mehran gholamin tel: +98 51 37112343; fax: +98 51 37112343 reihaneh alsadat mahmoudian division of human genetics, immunology research center, avicenna research institute, mashhad university of medical sciences, mashhad, iran. mohammad reza abbaszadegan division of human genetics, immunology research center, avicenna research institute, mashhad university of medical sciences, mashhad, iran - medical genetics research center, medical school, mashhad university of medical sciences, mashhad, iran mohammad mahdi forghanifard 3: department of biology, damghan branch, islamic azad university, damghan, iran. meysam moghbeli division of human genetics, immunology research center, avicenna research institute, mashhad university of medical sciences, mashhad, iran. faezeh moghbeli department biology, mashhad branch, islamic azad university, mashhad, iran.

background: human cripto-1, a member of the egf-cfc family, is involved in embryonic development, embryonic stem cell maintenance, and tumor progression. it also participates in multiple cell signaling pathways including wnt, notch, and tgf-β. remarkably, it is expressed in cancer stem cell (csc) compartments, boosting tumor cell migration, invasion, and angiogenesis. although cripto-1 is overe...

2016
David B. Landau Laura Hughes Angela Baker Andrew T. Bates Michael C. Bayne Nicholas Counsell Angel Garcia-Alonso Susan V. Harden Jonathan D. Hicks Simon R. Hughes Marianne C. Illsley Iftekhar Khan Virginia Laurence Zafar Malik Helen Mayles William Philip M. Mayles Elizabeth Miles Nazia Mohammed Yenting Ngai Emma Parsons James Spicer Paula Wells Dean Wilkinson John D. Fenwick

PURPOSE To report toxicity and early survival data for IDEAL-CRT, a trial of dose-escalated concurrent chemoradiotherapy (CRT) for non-small cell lung cancer. PATIENTS AND METHODS Patients received tumor doses of 63 to 73 Gy in 30 once-daily fractions over 6 weeks with 2 concurrent cycles of cisplatin and vinorelbine. They were assigned to 1 of 2 groups according to esophageal dose. In group ...

2013
Hui-Yu Chang Hua Jiang Fang Zhou

Multiple primary malignancies are not rare. While metachronous triple cancers are rare and a triple tumor case involving maxillary sinus and tympanic membrane is exceptionally rare. We present such an extremely rare case with the index tumor of adenoid cystic carcinoma of the maxillary sinus and 14 years later esophageal cancer was observed as a metachronous tumor. One year after esophageal can...

2011
Minoru Fukuchi Shinji Sakurai Masaki Suzuki Hiroshi Naitoh Yuichi Tabe Takaharu Fukasawa Shinsuke Kiriyama Takehiko Yokobori Hiroyuki Kuwano

We report a case of esophageal squamous cell carcinoma (SCC) with marked eosinophil infiltration which was identified postoperatively in the esophageal wall in areas not surrounding the SCC. The eosinophil infiltration was seen in the submucosa, muscle and adventitia, but not in the mucosa. Eosinophilic esophagitis (EoE) is a pathological condition defined as eosinophil infiltration within the ...

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