Aim. Little is known about the usefulness of narrow band imaging (NBI) for surveillance of patients after chemoradiotherapy for esophageal neoplasia. Its usefulness in detecting esophageal squamous cell carcinoma (SCC) or high-grade intraepithelial neoplasia (HGIN) in these patients was retrospectively compared to Lugol chromoendoscopy. Patients and Methods. We assessed the diagnostic ability o...

Epidemiological studies have demonstrated an association between human esophageal cancer and dietary/nutritional risk factors in developing countries. We examined the expression of p53 protein in 51 cases of esophageal squamous cell carcinomas (ESCCs) and paired normal esophageal tissues by immunohistochemistry. Alterations in the tumor suppressor gene p53 (exons 5-8) were analyzed in 51 cases ...

Most cases of esophageal cancer and colorectal cancer in Taiwan are diagnosed in the advanced stage and treated by surgery or concurrent chemoirradiation. The detection rates of early esophageal cancer and early colorectal cancer are still low in Taiwan. Metachronous early esophageal cancer and early colorectal cancer have rarely been reported. Endoscopic mucosal resection (EMR) is a well-estab...

Esophageal cancer is the sixth most common cause of cancer death in the world [1]. Over 80% of esophageal cancers occur in developing countries [1], and in these areas, 90% of these cancers are esophageal squamous cell carcinoma (ESCC) [2]. The precursor lesion of ESCC is squamous intraepithelial neoplasia (squamous dysplasia), defined histologically as nuclear atypia (enlargement, pleomorphism...

Bilateral sectioning of the esophageal nerves that innervate the gut of Aplysia was found to have profound effect on response decrement to inedible food: Time to criterion for cessation of feeding was elevated, no memory of the decrement was present 24 hr after training, and motor patterning during training was altered. The parametric features of response decrement to sustained lip stimulation ...

Geographic differences in exposure to suspected carcinogens have been identified in esophageal carcinogenesis, and both p53 alterations and human papillomavirus (HPV) infection have been reported in esophageal squamous carcinoma (ESC) from high-risk areas, including China and South Africa. The status of p53 alterations and HPV infection in ESC has not been determined in northern Italy, where th...

Vascular endothelial growth factors (VEGF)-A, -C and -D are members of the proangiogenic VEGF family of glycoproteins. VEGF-A is known to be the most important angiogenic factor under physiological and pathological conditions, while VEGF-C and VEGF-D are implicated in the development and sprouting of lymphatic vessels, so called lymphangiogenesis. Local tumor progression, lymph node metastases ...

BACKGROUND Radiofrequency ablation is extensively used to achieve pulmonary veins isolation for the cure of atrial fibrillation. Luminal esophageal temperature can be monitored by means of suitable probes to prevent the onset of lesions. OBJECTIVE To compute the thermal field generated by the ablation, to investigate the interaction between the electromagnetic field and the probe sensors, and...

We would like to congratulate Drs. Zullo et al on their publication reporting a rare case of mantle cell lymphoma (MCL) with esophageal involvement [1]. We strongly agree with them that, while gastrointestinal tract involvement is quite common in MCL, the esophagus is an extremely rare location. Zullo et al mentioned in their paper that the endoscopic features of MCL with esophageal involvement...

A 42-year-old male presented with 2 months history of progressive dysphagia predominantly to solids. Computed tomography of the chest showed a large subcarinal lymph node (Fig. 1). His PPD skin test was positive (32 mm x 30 mm). He underwent gastroduodenoscopy where a submucosal bulge with normal overlying mucosa causing luminal narrowing was noted in mid-esophagus. Endoscopic ultrasound (EUS) ...