نتایج جستجو برای: esculetin

تعداد نتایج: 200  

2017
Younghwa Kim Junsoo Lee

This study was conducted to investigate the anti-adipogenic activity of esculetin (ECT) which is reported to be attributable to the modulation of antioxidant enzymes during adipogenesis. After six days of ECT treatment of 3T3-L1 cells, lipid accumulation was determined by Oil red O staining. The levels of glutathione (GSH) and reactive oxygen species (ROS), and the activities of antioxidant enz...

Journal: :Annals of the rheumatic diseases 2001
S Elliott A D Rowan S Carrère P Koshy J B Catterall T E Cawston

OBJECTIVE To determine if a new inhibitor, esculetin (EST), can block resorption of cartilage. METHODS Interleukin 1alpha (IL1alpha, 0.04-5 ng/ml) and oncostatin M (OSM, 0.4-50 ng/ml) were used to stimulate the release of proteoglycan and collagen from bovine nasal cartilage and human articular cartilage in explant culture. Proteoglycan and collagen loss were assessed by dimethylmethylene blu...

2009
Kumar Sharma Balaram Ghosh Ulaganathan Mabalirajan Amit Kumar Dinda Surendra Kumar Sharma

Journal: :Pharmaceutical fronts 2021

Abstract The outbreak of novel coronavirus pneumonia (COVID-19), defined as a worldwide pandemic, has been public health emergency international concern. Pudilanxiaoyan oral liquid (PDL), an effective drug Traditional Chinese Medicine (TCM), is considered to be and alternative means for clinical prevention COVID-19. purpose this study was identify potential active constituents PDL, explore its ...

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