نتایج جستجو برای: erythrocytosis

تعداد نتایج: 780  

2017
Roberta Troia Chiara Agnoli Federico Fracassi Giuliano Bettini Alessandra Sfacteria Luciano Pisoni Francesco Dondi

This report documents a case of secondary inappropriate erythrocytosis in a cat with renal cell adenocarcinoma, its stabilization through manual erythrocytapheresis, and the EPO-immunostaining on the affected kidney. An 11-year-old cat was presented with lethargy, weight loss and polyuria/polydipsia. An abdominal mass was detected upon physical examination. Clinicopathological work-up revealed ...

2005
Keisuke Toyama Noritoyo Fujiyama Hiroshi Suzuki T. P. Chen Norikazu Tamaoki Yoshito Ueyama

Erythropoietin was measured by exhypoxic polycythemic mouse method in the course of a 64-yr-old male with renal cell carcinoma associated with erythrocytosis. Serum erythropoietin fluctuated with progression of the disease. Preoperative elevated erythropoietin (0.1 1 U/mI. p < 0.05) subsided after nephrectomy and again increased with developing lung metastasis (0.1 U/mI, p < 0.02). Erythropolet...

Journal: :The Japanese Journal of Gastroenterological Surgery 1999

Journal: :Baylor University Medical Center Proceedings 2020

Journal: :Hematology. American Society of Hematology. Education Program 2009
Mary Frances McMullin

Erythrocytosis results when there is an increased red cell mass and thus an increased hemoglobin. The causes can be divided into primary intrinsic defects of the erythroid progenitor cell and secondary defects, where factors external to the erythroid compartment are responsible. Both can then be further divided into congenital and acquired categories. Congenital causes include mutations of the ...

Journal: :Blood 2002
Michael S Wiesener Melchior Seyfarth Christina Warnecke Jan Steffen Jürgensen Christian Rosenberger Neil V Morgan Eamonn R Maher Ulrich Frei Kai-Uwe Eckardt

The von Hippel-Lindau (VHL) tumor suppressor gene targets hypoxia-inducible transcription factors (HIFs) for proteasomal degradation. Erythrocytosis due to inappropriate production of erythropoietin (EPO), one of the HIF target genes, is a classic albeit rare finding in patients with renal cancer. We report the clinical to molecular analysis in a patient in whom a thrombotic myocardial infarcti...

Journal: :Blood 1978
G C Bagby K Richert-Boe R D Koler

In 1954 a then 31-yr-old male was found to have erythrocytosis. Over the ensuing decade he received 72 mCi32P. In 1964 his daughters were found to have erythrocytosis. Further investigation led to the discovery of hemoglobin Yakima, a variant with high oxygen affinity. He received no further therapy and was well until 1975, when he developed the preleukemic syndrome. Within 12 mo. he developed ...

Journal: :Blood 1999
S S Watowich X Xie U Klingmuller J Kere M Lindlof S Berglund A de la Chapelle

Inherited mutations in the erythropoietin receptor (EPOR) causing premature termination of the receptor cytoplasmic region are associated with dominant familial erythrocytosis (FE), a benign clinical condition characterized by hypersensitivity of erythroid progenitor cells to EPO and low serum EPO (S-EPO) levels. We describe a Swedish family with dominant FE in which erythrocytosis segregates w...

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