Background: Lead (Pb) is one of the most important environmental pollutants that affect the male reproductive system. The aim of this study was to investigate the protective effect of green tea extract on lead-induced oxidative stress, apoptosis and morphometric changes in male mouse epididymis. Materials and Methods: Forty adult male mice were randomly divided into four groups (n= 10), as foll...

aflatoxins are toxic compounds which are produced by aspergillus flavus and a. parasiticus. these toxins can be transmitted into the animal body via contaminated feed. when these toxins enter the animal body, they can penetrate into different tissues. one of the most important tissues which can be influenced by aflatoxin is the mammary gland. milk protein is one the most important factors in de...

3D culture of patient-derived tumour tissue offers a route to personalized cancer treatment whereby potential drugs can be screened ex vivo stratify the optimal care plans. Such stratification predict patient responsiveness and adverse effects, with view streamlining first-line drug selection. Appropriate models need show biomimicry in biology origin, replicating relevant architecture, biomarke...

recent reports have indicated different effects of immunostimulatory sequences containing cpg-oligodeoxynucleotides (odn) on various immune cells. however, the exact role of cpg-odn in the human gut is unclear. in the present study, we assessed potential effects of cpg-odn on non lymphoid cell (intestinal epithelial cell line ht-29) on a dose-response and time-course basis. intestinal epithelia...

background: the aim of the present study was to evaluate the efficacy of autologous serum eye drop in treatment of recurrent corneal epithelial defect. m aterials and methods: fourteen patients with recurrent corneal epithelial defect were studied. autologous serum was prepared from the patients and diluted in 20% normal saline. the patients were instructed to use the autologous serum every six...

Epithelial tissue is a type that mainly covers the surfaces of body and organs. Most epithelial tissues are composed highly proliferative cells, necessitating robust stem cell activity. also most common site cancers. Therefore, identifying cells their self-renewal mechanisms prerequisite for promoting homeostasis, understanding cancer pathogenesis, developing regenerative therapy prevention. Ov...

Abstract Idiopathic pulmonary fibrosis (IPF) is a serious and irreversible chronic lung disease. Bleomycin (BLM) an anticancer drug, which can cause severe toxicity. The main target of oxidative stress-induced injury alveolar epithelial cells, lead to interstitial fibrosis. present study investigated whether hispidin (HP), has excellent antioxidant activity, attenuates bleomycin-induced via ant...

Objective(s): Endometriosis is a complex gynecologic disease with unknown etiology. Noscapine has been introduced as a cancer cell suppressor. Endometriosis was considered as a cancer like disorder, The aim of present study was to investigate noscapine apoptotic effect on human endometriotic epithelial and stromal cells in vitro. Materials and Methods:In this in vitro study, endometrial biopsie...