Clove bud essential oil (CEO) and its major individual phenolic constituent eugenol were formulated as nanoparticles in water-based microemulsion systems. The oil titration method was used to incorporate different amounts of the oil and eugenol in the micellar solution of Tween-20. The Antioxidant and antimicrobial activities were evaluated using the DPPH* free radical scavenging assay and the ...

Present study describes microencapsulation of eugenol using gelatin-sodium alginate complex coacervation. The effects of core to coat ratio and drying method on properties of the eugenol microcapsules were investigated. The eugenol microcapsules were evaluated for surface characteristics, micromeritic properties, oil loading and encapsulation efficiency. Eugenol microcapsules possessed good flo...

Caffeic acid O-methyltransferase (COMT) methylates N-acetylserotonin into melatonin; that is, it has N-acetylserotonin O-methyltransferase (ASMT) activity. The ASMT activity of COMT was first detected in Arabidopsis thaliana COMT (AtCOMT). To confirm the involvement of COMT on melatonin synthesis in other plant species, the ASMT activity of a COMT from rice (Oryza sativa) (OsCOMT) was evaluated...

Department of Pharmacology, Objective: To investigate the antinociceptive potential of eugenol on different pain models Bharati Vidyapeeth Deemed in mice. University, Poona College of Pharmacy, Materials and Methods: Eugenol was evaluated (1-100 mg/kg, i.p.) in various Pune 411 038. experimentally induced pain models like, formalin induced hyperalgesia, acetic acid *Present Address: Discovery i...

The Phenolate Cement Zinc oxide-eugenol cements have always been regarded as the blandest in terms of their effect on the dental pulp. For this reason, these materials were commonly used as the control in biocompatibility pulp research studies on cements and restorative materials. Zinc oxide-eugenol cements have traditionally been used as temporary restoratives because of the sedative effect on...

Authors' A University Manches 3Neurosug NHS Trus Developme Urology, N

The present study investigated the possibility that different aspects of performance monitoring share a common dopaminergic foundation. For this purpose we analyzed the influence of the COMT Val(158)Met polymorphism on electrophysiological markers of conflict and error monitoring, respectively. An EEG was recorded while 65 healthy subjects completed a response-conflict evoking task. In the even...

Treatment of chloroethylnitrosourea-resistant cells with streptozotocin (STZ) prior to bis-chloroethylnitrosourea (BCNU) exposure has been shown to result in a depletion of O6-methylguanine DNA methyltransferase (MGMT) activity, increased BCNU-induced interstrand cross-linking, and a 2-3 log enhancement of BCNU cytotoxicity in vitro. The current study was undertaken to define the kinetics of re...

Eugenol is widely used in dentistry to relieve pain. We have recently demonstrated voltage-gated Na(+) and Ca(2+) channels as molecular targets for its analgesic effects, and hypothesized that eugenol acts on P2X(3), another pain receptor expressed in trigeminal ganglion (TG), and tested the effects of eugenol by whole-cell patch clamp and Ca(2+) imaging techniques. In the present study, we inv...

AIMS AND OBJECTIVES The aim of this study was to assess the outcome of eugenol-free and eugenol-containing cements on the bond strength of resin cement. MATERIALS AND METHODS Dentin was exposed in five groups of extracted teeth (20 specimens each). In Group 1, specimens were not given temporary cementation. In Groups 2 and 3, specimens were given temporary restoration fixed with eugenol-free ...