One of the DNA repair machineries is activated by Poly (ADP-ribose) Polymerase (PARP) enzyme. Particularly, this enzyme is involved in repair of damages to single-strand DNA, thus decreasing the chances of generating double-strand breaks in the genome. Therefore, the concept to block PARP enzymes by PARP inhibitor (PARPi) was appreciated in cancer treatment. PARPi has been designed and tested f...

An efficient conversion of lignocellulose into fermentable sugars is a key step in producing bioethanol in a cost effective and eco-friendly manner. Alternative source like water hyacinth biomass (WHB) (Eichhornia crassipes) may be used as a supplement for the routine feedstocks. The enzyme loading for optimum yield of total reducing sugar was investigated and the enzyme-substrate interaction o...

Hydrogen gas is a potential renewable alternative energy carrier that could be used in the future to help supplement humanity's growing energy needs. Unfortunately, current industrial methods for hydrogen production are expensive or environmentally unfriendly. In recent years research has focused on biological mechanisms for hydrogen production and specifically on hydrogenases, the enzyme respo...

Group transfer reactions catalyzed by enzymes have assumed a position of intense interest in contemporary enzymology (1). Well known examples of radicals capable of being transferred in such reactions are methyl, glycosyl, aeetyl, phosphoryl, pept,idyl, nucleosidyl, and nucleotidyl, in addition to the transport of hydrogen as seen with the familiar nuoleot.ide coenzymes. In this paper we wish t...

Ellagic acid (EA) has been reported to have various beneficial pharmacological properties, including strong antidiabetic activity. Glycation plays an important role in diabetesassociated complications. In this study, we have investigated the antiglycating potential of EA by using the important antioxidant enzyme, superoxide dismutase (SOD). The glycation of SOD by glucose or methyglyoxal (MG) a...

The development of specialized sports nutrition with components collagen-containing fish raw materials is due to the shortage domestic products this group, problem waste processing, scientific data on bioactive peptides marine origin. Low-molecular active and protein-mineral compositions in form powder liquid dietary supplements were obtained from scales sardine sardinella by methods deep hydro...

the aim of the present study was to examine the effect of aerobic training and green tea supplementation on serum leptin and insulin resistance in overweight and obese men. for this purpose, 43 overweight and obese men were selected voluntarily and were included in four groups: control (body mass index 31.4+3.7, vo2max 39.3+3.8 ml/kg.min), green tea supplement (body mass index, 30.3±2.8 k/m2, v...

As β-glucosidases represent the major bottleneck for industrial degradation of plant biomass, great efforts are being devoted to discover both novel and robust versions these enzymes, as well develop efficient inexpensive ways produce them. In this work, raw glycerol from chemical production biodiesel was tested carbon source fungus Talaromyces amestolkiae with aim producing enzyme β-glucosidas...