Wheat straw is a sufficient agricultural by-product with a low market price. The biofuel produced from lignocellulosic material exhibits energetic, economic and environmental benefits in contrast to bio-ethanol from starch or sugar. Until now, physical and chemical difficulty caused by the close connection of the main components of lignocellulosic biomass, discourage the hydrolysis of cellulose...

anaerobic digestion is a feasible technology to stabilize the solid waste generated inslaughterhouses obtaining significant quantities of biogas, considered as a clean and renewable fuel. this iswhy it is important to optimize the digestion process in order to eliminate organic matter and maximize theproduction of biogas. in this work, a system was developed for treating slaughterhouse solid wa...

drying is one of the most important steps in raisin processing. during this step, initial moisture content decreases up to 15-17% (db) for suitable storage. achieving optimum drying conditions can affect the processing time and improve raisin quality. temperature, air velocity and pretreatment are important factors in the quality of the grape drying process. in this research, the effect of temp...

The recalcitrance of cellulosic biomass, the only abundant, sustainable feedstock for making liquid fuels, is a primary obstacle to low cost biological processing, and development of more easily converted plants and more effective enzymes would be of great benefit. Because no single parameter describes recalcitrance, superior variants can only be identified by measuring sugar release from plant...

BACKGROUND Pretreatment is essential to realize high product yields from biological conversion of naturally recalcitrant cellulosic biomass, with thermochemical pretreatments often favored for cost and performance. In this study, enzymatic digestion of solids from dilute sulfuric acid (DA), ammonia fiber expansion (AFEX™), and ionic liquid (IL) thermochemical pretreatments of corn stover were f...

Moderate loadings of cellulase enzyme supplemented with beta-glucosidase were applied to solids produced by ammonia fiber expansion (AFEX), ammonia recycle (ARP), controlled pH, dilute sulfuric acid, lime, and sulfur dioxide pretreatments to better understand factors that control glucose and xylose release following 24, 48, and 72 h of hydrolysis and define promising routes to reducing enzyme d...

BACKGROUND The use of the enzymatic hydrolysis of lignocellulose with subsequent fermentation to ethanol provides a green alternative for the production of transportation fuels. Because of its recalcitrant nature, the lignocellulosic biomass must be pretreated before enzymatic hydrolysis. However, the pretreatment often results in the formation of compounds that are inhibitory for the enzymes o...

DNA topoisomerases (topo) are the cellular targets of several anticancer drugs used today in the clinic. Our previous work demonstrated that certain tyrphostin derivatives, known as protein tyrosine kinase antagonists, are catalytic inhibitors of DNA topoisomerases I (topo I) in vitro. In this study, we examined the ability of tyrphostin derivatives to affect the activity of topo I in the cell ...

Background Lignocellulosic biomass is an important resource for renewable production of biofuels and bioproducts. Enzymes that deconstruct this biomass are critical for the viability of biomass-based biofuel production processes. Current commercial enzyme mixtures have limited thermotolerance. Thermophilic fungi may provide enzyme mixtures with greater thermal stability leading to more robust p...

Adenylate cyclase activity was investigated in either homogenate or particulate fractions from the frontal cerebral cortex of the gerbil following five experimental conditions of bilateral ischemia. After periods of 15 min ischemia, 15 min ischemia plus 15 min of recirculation or 60 min ischemia the enzyme generally displayed enhanced responses to GTP, norepinephrine (NE), dopamine (DA), NE + G...