PURPOSE To evaluate whether photorefractive keratectomy (PRK) for moderate myopia using a solid-state laser with a wavelength of 213 nm alters the corneal endothelial cell density. SETTING University refractive surgery center. METHODS The corneal endothelium was analyzed preoperatively and 1, 6, and 12 months postoperatively using corneal confocal microscopy (modified HRT II with a Rostock ...

Objective: To investigate the value of CTC clinical features and blood-related test indicators in renal cancer patients by detecting number circulating tumor cells (CTC) with cancer. Methods: analyze 59 cell carcinoma (RCC) admitted to Department Urology, Affiliated Hospital Chengde Medical College from May 2018 October 2019. According count (5 pcs/3.5 ml), they were divided into positive group...

The underlying mechanisms behind the effect of atorvastatin on patients with coronary slow flow (CSF) remain largely unknown. To investigate the possible underlying molecular mechanisms 108 patients were divided into atorvastatin group and control group. Coronary flow was quantified according to corrected TIMI frame count (CTFC). Serum high sensitivity C-reactive protein (hs-CRP), lipids, ET-1,...

conclusions end stage renal disease (esrd) have accelerated inflammatory conditions. simvastatin clearly lowers the serum levels of crp and il-6, and the white blood cell count in dialysis patients. administering simvastatin to dialysis patients is safe. results at baseline, each of treatment and control groups had similar characteristics. during the study, the average level of crp decreased in...

introduction: some studies have demonstrated the potential of herbal drugs for the treatment of various diseases associated with impaired vascular nitric oxide (no). for diagnosis of the mechanism of these herbal plants, it seems necessary to evaluate the herbal extracts on the endothelium cell. the aim of the study was to investigate the effect of extract of trigonella foenum-graecum (t.foenum...

BACKGROUND Recent studies have shown that endothelial proliferation and angiogenic response are characteristic of degenerative events, such that the magnitude of endothelial activation is reflective of the progression of neurodegeneration. PURPOSE This study sets out to, compare, the degenerative changes seen in the parietal cortex (PC) and periventricular zone (PVZ) after cyanide toxicity or...

kcnk2 was previously shown to regulate immune-cell trafficking into the central nervous system (cns). kcnk2-/- mice demonstrated a more severe disease course in experimental autoimmune encephalomyelitis, an animal model of multiple sclerosis, due to an increased immune-cell migration into the cns. an upregulation of the cellular adhesion molecules icam1 and vcam1 on brain endothelial cells in k...

Purpose: To correlate corneal endothelium cell density with dry eye disease compared to an age-matched control group. Materials and Methods: In this cross-sectional study, a total of 150 eyes of 75 female students aged 19-25 years who did not have any history of eye injuries or eye disease affecting the corneal endothelium cell density, were recruited from KSU Female Campus. They were divided i...

introduction: endothelial cells are subjected to mechanical forces caused by pulsatile flow and pressure leading to hemodynamic shear stress and circumferential stress on endothelial layer. the study aimed at a quantitative evaluation of endothelial cell morphology by application of cyclic loading. endothelial cells respond to applied loads with adaptation and remodeling. such mechanisms are ma...

To improve well-known titanium implants, pores can be used for increasing bone formation and close bone-implant interface. Selective Laser Melting (SLM) enables the production of any geometry and was used for implant production with 250-µm pore size. The used pore size supports vessel ingrowth, as bone formation is strongly dependent on fast vascularization. Additionally, proangiogenic factors ...