Recently, p16 stromal expression has been reported in the examination of endometrial serous adenocarcinomas associated with polyps. Therefore, polyps are defined as preneoplastic formations some textbooks. Due to these different expressions cells polyps, we wanted present place tissue hyperplasia and differential diagnosis our review article.

•Endometrial stromal sarcoma (ESS) may have sex cord differentiation, usually focal.•Diagnosis of ESS is difficult when variant morphology predominates.•Prognosis differs between ESS and UTROSCT; therefore, distinction is critical.•Extensive tumor sampling is mandatory to identify neoplastic endometrial stroma.•Sex cord differentiation may be associated with endometrial hyperplasia.

Objective: To evaluate the reliability and accuracy of frozen section (FS) compared with final pathology and to determine whether they should be obligatory in every patient with atypical endometrial hyperplasia (AEH). Methods: We retrospectively assessed the medical records of 192 patients whose endometrial biopsy results were endometrial hyperplasia and underwent hysterectomy at our center. Re...

AIM To evaluate the treatment of endometrial hyperplasia (EH) with different progestins. METHODS Eighty-two women with simple EH without atypia were included. Patients were offered oral progestagens and were randomized to one of three options for 3 months: medroxyprogesterone acetate (MPA, 10 mg/day), lynestrenol (LYN, 15 mg/day) and norethisterone (NET, 15 mg/day) for 10 days per cycle. Pati...

OBJECTIVE The aim of the study was to investigate the prevalence of endometrial polyps in patients with uterine fibroids and associated factors of coexistence of these two pathologies. MATERIALS AND METHODS The medical records of 772 patients who underwent hysterectomy because of uterine fibroids were retrospectively reviewed. Patients were divided into two groups according to the presence of...

INTRODUCTION Endometrial hyperplasia is a precancerous lesion of the endometrium, commonly presenting with uterine bleeding. If managed expectantly, it frequently progresses to endometrial carcinoma, rates of which are increasing dramatically worldwide. However, the established treatment for endometrial hyperplasia (progestogens) involves multiple side effects and leaves the risk of recurrence....

UNLABELLED The aim, of this prospective study was to estimate whether the presence of endometrial fluid detected by transvaginal ultrasound investigation was a marker for the pathological changes of the endometrium in postmenopausal women. MATERIAL AND METHODS 128 postmenopausal women with uterine bleeding and 29 asymptomatic postmenopausal women underwent transvaginal ultrasound investigatio...

Objectives: To evaluate the value of endometrial sampling and histopathology for asymptomatic postmenopausal women with endometrial thickness >!5mm. Population: Two hundred sixty one asymptomatic postmenopausal women with thick endometrium >!5mm accidentally discovered during investigations for reasons other than vaginal bleeding. Method: Cases with confirmed thick endomertrium >!5mm by TVS und...