Metal–organic frameworks (MOFs), as high-surface-area materials, have shown promise in various areas of application, such chiral sensing and separation, due to their flexibility design organized porous cages. Researchers been striving develop high-performance enantiorecognition separation analytical techniques science fields. The main aim this review is provide a comprehensive overview chiralit...

The enantiomeric separation of antifungal compounds is an arduous task in pharmaceutical and biomedical fields due to the different properties that each diastereoisomer presents. enantioseparation a group fungicides (sulconazole, bifonazole, triadimefon triadimenol) using supercritical fluid chromatography was achieved this work. For goal, four chiral columns based on polysaccharide derivatives...

one of the problems encountered in ce separations of basic compounds is the adsorption of analytes onto the negatively charged capillary wall which could lead to poor repeatability of migration time and peak area. additionally, separation of enantiomers of chiral of basic drugs is commonly carried out in low ph buffer which contributes to strong ionic interaction of the cationic drug ions with ...

Abstract Regioselective tritylation and carbonate aminolysis were employed in this work to synthesize cellulose 2,3- bis (3,5-dimethylphenyl carbamate)-6-( α -phenylethyl carbamate)-type chiral selectors. We evaluated optimized the critical aspects of regioselective detritylation at C6 glucopyranose units polysaccharide backbone. The advantage using II comparison I for was analyzed time determi...

Micellar electrokinetic chromatography (MEKC), one of the major capillary electrophoresis (CE) modes, has been interfaced to mass spectrometry (MS) to provide high sensitivity and selectivity for analysis of chiral compounds. The research in this dissertation presents the development of novel polymeric glucopyranoside based molecular micelles (MoMs) (aka. polymeric surfactants) and their applic...