نتایج جستجو برای: emulsion solvent diffusion

تعداد نتایج: 226762  

2015
PRAVIN GUPTA MANISH KUMAR NARSINGH SACHAN

Objective: The present work was to formulate buoyant system in order to protect the drug from gastric acid degradation, increasing the gastric residence time, control the drug leaching by use of enteric polymers, prolong the half life for longer duration of action, furthermore to prevent dosage form adherence to the mucous wall in order to avoid incomplete drug release. Moreover the side effect...

Journal: :iranian journal of pharmaceutical research 0
mitra jelvehgari department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. drug applied reseach center, tabriz university of medical sciences, tabriz, iran. davoud hassanzadeh department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. drug applied research center, tabriz university of medical sciences, tabriz, iran. farhad kiafar department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. badir delf loveymi department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran. sara amiri department of pharmaceutics, faculty of pharmacy, tabriz university of medical sciences, tabriz, iran.

the objective of this study was to formulate and evaluate the drug-polymer interaction of mefenamic acid (ma) using two polymers with different characteristics as ethylcellulose (ec) and/or cellulose acetate phthalate (cap). microspheres were prepared by the modified emulsion solvent evaporation (mese). the effect of drug-polymer interaction was studied for each of microspheres. important param...

A Box-Behnken design with three replicates was used for preparation and evaluation of Eudragit vancomycin (VCM) nanoparticles prepared by double emulsion. The purpose of this work was to optimize VCM nanoparticles to improve the physicochemical properties. Nanoparticles were formed by using W1/O/W2 double-emulsion solvent evaporation method using Eudragit RS as a retardant material. Full factor...

2006
JIA Yuxiang

The diffusion behavior of methanol in different critical media (n-pentane, n-hexane, n-heptane and acetone) was investigated by the Monte Carlo (MC) method. From the simulation results, the diffusion constant of methanol molecule in the critical n-hexane is much larger than those in n-pentane, n-heptane and acetone. By analyzing the microscopic configurations of the critical mixtures, it is fou...

2013
Yang Yuan Zhili Wan Shouwei Yin Xiaoquan Yang

To fabricate a soy protein emulsion with good storage stability against microorganisms, we investigated the stability and antimicrobial activity of a b-conglycinin (7S) and chitosan (CS) mixed emulsion at acidic pHs. Results of droplet size and microstructure showed that 7S/CS mixed emulsions were stable at acidic pHs while the 7S emulsion was not. As for the storage test, results showed that t...

Journal: :Indian Journal of Pharmaceutical Sciences 2022

Microspheres containing indinavir sulfate were prepared by the emulsion solvent evaporation technique using surfactant sorbitan monooleate 80. The evaluation reports for Fourier-transform infrared spectroscopy and X-ray diffraction taken to see whether altered physicochemical features of produced microspheres. Scanning electron microscopy was used observe surface topography When 80 employed at ...

Journal: :International Journal of Health Sciences (IJHS) 2022

The present work was performed with the objective of novel topical formulation development poorly water-soluble drug Diclofenac diethylamine by loading drug-containing nanosponge into formulation. nanosponges are polymeric nanoparticles that entrap drug. drug-loaded has different absorption characteristics in comparison to pure delivery system. Methods: first loaded ethylcellulose using emulsio...

Journal: :AJNR. American journal of neuroradiology 2004
Hak J Kim Chang H Lee Hae G Kim Sang D Lee Suk M Son Yong W Kim Choong K Eun Seung M Kim

BACKGROUND AND PURPOSE Clinical cerebral-fat embolism shows both reversible and irreversible changes. We used MR imaging to investigate the reversibility of embolized lesions induced with a fat-emulsion technique and to evaluate the histologic findings. METHODS A fat emulsion was made with 0.05 mL of triolein and 20 mL of normal saline and vigorous to-and-fro movement through a three-way stop...

2008
Vivian Saez José Ramón Hernández Carlos Peniche

Microencapsulation of peptides and proteins has recently become a relevant alternative to develop novel drugdelivery systems. Among techniques designed to microencapsulate substances of different nature, the interfacial polymerization, spray-drying and solvent evaporation techniques are those most widely studied for encapsulation of biomolecules. The solvent double emulsion-evaporation procedur...

2012
Jia-Ying Xin Yan Wang Tie Liu Kai Lin Le Chang Chun-Gu Xia

Esterification of starch was carried out to expand the usefulness of starch for a myriad of industrial applications. Lipase B from Candida antarctica, immobilized on macroporous acrylic resin (Novozym 435), was used for starch esterification in two reaction systems: micro-solvent system and solvent-free system. The esterification of corn starch with palmitic acid in the solvent-free system and ...

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