BACKGROUND Atropine has been used as a successful primary medical treatment for hypertrophic pyloric stenosis. Several authors have reported a higher rate of incomplete pyloromyotomy with the laparoscopic approach compared to open. In this study, we evaluated the use of atropine as a medical treatment for infants with emesis persisting greater than 48 hours after a laparoscopic pyloromyotomy. ...

The need to control chemotherapy-induced nausea and vomiting is continuously stimulating research to find better options for the optimal antiemetic care. Palonosetron is different from conventional serotonin receptor antagonists not only by the fact of having a longer half-life but also by higher binding affinity for serotonin receptors. It is the first agent in the class which is approved for ...

The side effects commonly experienced by patients receiving chemotherapy for the treatment of cancer can challenge many aspects of daily life. Nausea and vomiting, the most common side effects reported by patients, affect the ability to continue with usual life activities and, thus have a pronounced impact on quality of life. This paper reviews studies of the impact of nausea and emesis on qual...

CONTEXT Pertussis is often overlooked as a cause of chronic cough, especially in adolescents and adults. Several symptoms are classically thought to be suggestive of pertussis, but the diagnostic value of each of them is uncertain. OBJECTIVE To systematically review the evidence regarding the diagnostic value of 3 classically described symptoms of pertussis: paroxysmal cough, posttussive emes...

PURPOSE A previous study reported radiation protection from mucosal injury with D-methionine (D-met) in preclinical evaluation; therefore, the pharmacokinetics, safety, and utility of D-met were evaluated clinically. EXPERIMENTAL DESIGN The pharmacokinetics of D-met following oral administration of a bioavailable formulation (MRX-1024) was evaluated in normal volunteers. Subsequently, 25 pati...

PURPOSE To compare the antiemetic combination of palonosetron, dexamethasone, and aprepitant (PDA) with antiemetic combination of ondansetron and dexamethasone (OD) in head and neck cancer patients receiving docetaxel, carboplatin, and 5-FU based chemotherapy. METHODS Sixty previously untreated patients were randomly divided into two groups of thirty patients each. The PDA group received a co...

To the Editor: In the otherwise excellent review article "Anaesthesia and emesis, II" by Palazzo and Strunin, ~ the section devoted to metoclopramide is perhaps open to comment. Reference is made to Davies and Howells' paper on the ability of metoclopramide to empty the stomach following injury, 2 which did not differentiate between liquid and solid gastric content. Hancock 3 showed no differen...

Emesis gravidarum merupakan keluhan umum yang disampaikan kehamilan muda. Kehamilan menimbulkan perubahan hormonal pada wanita karena terdapat peningkatan hormon estrogen, progesteron dan dikeluarkan gonodotropine plasenta. Perubahan hormon-hormon inilah menyebabkan timbulnya gejala pusing mual muntah terutama trimester pertama. Jahe daun mint dapat mengurangi mengandung minyak atrisi memblokir...