The antigenic similarity between tumors and embryos has been appreciated for many years and reflects the expression of embryonic gene products by cancer cells and/or cancer-initiating stem cells. Taking advantage of this similarity, we have tested a prophylactic lung cancer vaccine composed of allogeneic murine embryonic stem cells (ESC). Naïve C57BL/6 mice were vaccinated with ESC along with a...

meningitis is an inflammation of the membranes that surround the brain and spinal cord, thereby involving the arachnoid, the pia and the cerebrospinal fluid (csf). it is divided into viral and bacterial meningitis. for different reasons the diagnosis of bacterial meningitis is very important. the examination of csf samples may provide information about causative microorganism. the sensivity of ...

In many arthropods, the appearance of new segments and their differentiation are not completed by end embryogenesis but continue, in different form degree, well after hatching, some cases up to last post-embryonic molt. Focusing on segmentation process currently described as segment addition (or, anamorphosis), we revise here current knowledge discuss it an evolutionary framework which involves...

considering the 50% mortality rate of neonatal septicemia associated with neutropenia and increasing resistance to antibiotics, simultaneous antibiotic therapy strategies are becoming more important. however, few studies have been performed to evaluate effectiveness of rhg-csf in the treatment of neutropenia in neonates. this randomized clinical trial was performed on 40 neutropenic neonates wi...

introduction: leakage of cerebrospinal fluid in the skull base may be accompanied with recurrent meningitis. the site of leakage may either be anterior (in the nose and paranasal sinuses) or posterior (in the temporal bone). various imaging techniques can be used to precisely locate the point of leakage but despite all the advances in imaging techniques there are still some rare cases in which ...

Background : Meningitis is more common during the neonatal period than other periods of life and has a prevalence of one in 1000 live births. The similarity of its clinical manifestations with other infectious diseases makes it difficult to diagnose. The aim of the current study was to determine the relationship between age, sex, clinical signs and symptoms and laboratory test results of ne...

Background Effects of GCSF (Granulocyte Colony-stimulating Factor) injection in patients suffering from recurrent pregnancy loss has been studied in some studies and we now know that transvaginal perfusion of G-CSF might be helpful for improvement of implantation rate among patients with thin endometrium and patients under in vitro fertilization /embryo transfer (IVF/ET) or intracytoplasmic spe...

Since the 2013 description of Blastomyces gilchristii, research describing the virulence or clinical outcome of B. gilchristii infection has been lacking. We report molecular evidence of B. gilchristii as an etiologic agent of fatal acute respiratory distress syndrome. B. gilchristii infection was confirmed by PCR and sequence analysis.

the production of colony-stimulating factors (csf) is delicately controlled through a complex network of humoral and environmental factors. we have studied some of the mechanisms which regulate the production of csf as compared to general protein synthesis in the lung tissue ill vitro. when lung tissue from mice was cultured for various times in serum free medium, the first detectable level of ...