The effect of mechanical strain on the binding energy of adsorbates to late transition metals is believed to be entirely controlled by electronic factors, with tensile stress inducing stronger binding. Here we show, via computation, that mechanical strain of late transition metals can modify binding at stepped surfaces opposite to well-established trends on flat surfaces. The mechanism driving ...

The contractile state of the left ventricle in man was analyzed by correlating left ventricular (LV) dimensional changes during contraction determined from cineangiograms, with simultaneous measurements of LV pressure. The mechanical characteristics of ventricular contraction were expressed quantitatively by deriving the extent and velocity of circumferential fiber shortening at the midwafl and...

The erythropoietin (EPO) gene is one of the best examples of a mammalian gene controlled by oxygen tension. The DNA elements responsible for hypoxia-induced transcription consist of a short region of the proximal promoter and a <50-bp 3' enhancer. The elements act cooperatively to increase the transcriptional initiation rate approximately 100-fold in response to low oxygen tension in Hep3B cell...

"The connection between Schiller’s dramas and the reflections developed in his philosophical historical writings are a highly problematic question. Simplifying, it can be said that texts project Schillerian ideals ones reflect psychological knowledge of human beings. This tension ideal reality is manifested, among other constellations, absence. In Wallenstein Wilhelm Tell, leads out action for ...

Airborne particulate samples were collected from various reference sites in Hong Kong and the energy dispersive X-ray fluorescence (EDXRF) intensities for 19 chemical elements were recorded. Principal component analysis (PCA) was employed so that the variances of these 19 original variables were captured by a few new indices called principal components or PCs. Data points for similar sources we...

Traditionally, statistical summaries of categorical data often have been visualized using graphical plots of central moments (e.g., mean and standard deviation), or cumulants (e.g., median and quartiles) by box plots. In this work we reexamine the box plot and its relatives and develop a new hybrid summary plot that combines moment, cumulant, and density information. In view of the important ro...

Figure 1 shows an example of plot generated with GOsummaries package. All the GOsummaries plots have more or less the same layout, however, the elements are adjusted corresponding to the underlying analysis. The plot is built of components (Fig 1A) that represent a gene list or a pair of gene lists as in Fig 1. Each component is composed of two parts the word cloud(s) (Fig 1E), representing the...

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Kinesin advances 8 nm along a microtubule per ATP hydrolyzed, but the mechanism responsible for coordinating the enzymatic cycles of kinesin's two identical motor domains remains unresolved. Here, we have tested whether such coordination is mediated by intramolecular tension generated by the "neck linkers," mechanical elements that span between the motor domains. When tension is reduced by exte...