S. Devasenathipathy and J.G. Santiago The advent of microfabricated chemical analysis systems has led to a growing interest in microfabricated fluidic systems with characteristic scales in the range of a micron to a millimeter. A motivation to integrate components in a manner analogous to modern microelectronics is coupled with a potential for achieving massively parallel functions, and the fie...

Electrokinetic concentration devices based on the ion concentration polarization (ICP) phenomenon have drawn much attention due to their simple setup, high enrichment factor, and easy integration with many subsequent processes, such as separation, reaction, and extraction etc. Despite significant progress in the experimental research, fundamental understanding and detailed modeling of the preco...

This paper presents an innovative micro flow cytometer which is capable of counting and sorting cells or particles. This compact device employs electrokinetic forces rather than the more conventional hydrodynamic forces technique for flow focusing and sample switching, and incorporates buried optical fibers for the on-line detection of cells or particles. This design approach results in a compa...

The suitability of electrokinetic remediation for removing heavy metals from dredged marine sediments with high acid buffering capacity was investigated. Laboratory-scale electrokinetic remediation experiments were carried out by applying two different voltage gradients to the sediment (0.5 and 0.8 V/cm) while circulating water or two different chelating agents at the electrode compartments. Ta...

In case-control research where there are multiple case groups, standard analyses fail to make use of all available information. Multiple events case-control (MECC) studies provide a new approach to sampling from a cohort and are useful when it is desired to study multiple types of events in the cohort. In this design, subjects in the cohort who develop any event of interest are sampled, as well...

The electrokinetic process is an emerging technology for in situ soil contamination, in which chemical species, both ionic and nonionic are transported to an electrode in soil. These products are subsequently removed from the ground via collection systems engineered for each specific application. Electro kinetics refers to movement of water, ions and charged particles relative to one another un...

Scanning confocal fluorescence microscopy and multiphoton fluorescence microscopy were used to image the uptake of the protein lysozyme into individual ion exchange chromatography particles in a packed bed in real time. Self-sharpening concentration fronts penetrating into the particles were observed at low salt concentrations in all of the adsorbents studied, but persisted to 100 mM ionic stre...

Electrokinetic extraction is an emerging technology that has shown considerable potential for efficient and effective removal of both inorganic and organic contaminants from fine-grained soils of low hydraulic conductivity and large specific area when conditions are favorable. The cleanup technology is basically the application of a direct-current electric field across contaminated soils throug...

To detect biochemicals with ultrahigh sensitivity, efficiency, reproducibility, and specificity has been the holy grail in the development of nanosensors. In this work, we report an innovative type of photonic-plasmonic hybrid Raman nanosensor integrated with electrokinetic manipulation by rational design, which offers dual mechanisms that enhance the sensitivity for molecule detection directly...