Nuclear lamins form the major structural elements that comprise the nuclear lamina. Loss of nuclear structural integrity has been implicated as a key factor in the lamin A/C gene mutations that cause laminopathies, whereas the normal regulation of lamin A assembly and organization in interphase cells is still undefined. We assumed phosphorylation to be a major determinant, identifying 20 prime ...

Joining soft to hard materials is a challenging problem in modern engineering applications. In order alleviate stress concentrations at the interface between with such mismatch mechanical properties, use of functionally graded interphases becoming more widespread design new generation engineered composite materials. However, current macroscale models that aim mimicking behavior complex systems ...

One striking feature of chromatin organization is that chromosomes are compartmentalized into distinct territories during interphase, the degree of intermingling being much smaller than expected for linear chains. A growing body of evidence indicates that the formation of loops plays a dominant role in transcriptional regulation as well as the entropic organization of interphase chromosomes. Us...

A hybrid nanowire (HNW) was constructed by coating a single-wall carbon nanotube (SWCNT) with piezoelectric zinc oxide (ZnO). The two components of the HNW interact with each other via the van der Waals (vdW) force. This paper aims to study the effect of the piezoelectricity in the ZnO layer and the inter-phase vdW interaction on the fundamental vibration of the HNWs. In doing this, a new model...

conventional cytogenetic is the standard technique for detection of philadelphia (ph) chromosome in chronic myeloid leukemia (cml). evaluation of abelson murine leukemia/breakpoint cluster region (abl/bcr) fusion using dual-colour fluorescence in situ hybridization (d-fish) is an alternative approach allowing rapid and reliable detection of the disease. we employed the technique of interphase d...

abstract  background: mosaic form of turner syndrome that represented by two or more  cell lines in an affected individual, often has limitation for detection with classical  cytogenetic methods. the present study was carried out to compare the efficiency of  interphase fluorescence in situ hybridisation (fish) and cytogenetic techniques in  detection of mosaic form of turner syndrome.  methods...

Accurate degradation models are crucial to perform efficient battery design and management. The time resources required improve the output accuracy of depends critically on ability assess sensitivity input factors governing inherent dominant mechanism in model. Here, we present a analysis pseudo-two-dimensional model coupled with capacity fade based solid-electrolyte interphase (SEI) formation ...

The DNA structure checkpoint protein Rad26ATRIP is also required for an interphase microtubule damage response. This checkpoint delays spindle pole body separation and entry into mitosis following treatment of cells with microtubule poisons. This checkpoint requires cytoplasmic Rad26ATRIP, which is compromised by the rad26:4A allele that inhibits cytoplasmic accum...

 Abstract  Background: Mosaic form of turner syndrome that represented by two or more  cell lines in an affected individual, often has limitation for detection with classical  cytogenetic methods. The present study was carried out to compare the efficiency of  interphase Fluorescence In Situ Hybridisation (FISH) and cytogenetic techniques in  detection of mosaic form of turner syndrome.  Method...