Background: Progesterone is indispensable for differentiation of human endometrial stromal cells (HESCs) into decidual cells, a process that critically controls embryo implantation. However, HESCs also abundantly express androgen receptors (AR), yet the role of this member of the superfamily of ligand-dependent transcription factors in the decidual process remains poorly elucidated. Materials a...

Ectopic parathyroid adenomas can be a cause of recurrent and refractory hyperparathyroidism. Majority are located in the neck region, however very few cases they within mediastinum. In such excision via cervical approach is not possible it becomes diagnostic as well surgical challenge. Excision thoracoscopic preferred this regard. Here we represent case ectopic adenoma embedded thymus gland whi...

cesarean scar pregnancy (csp) is a rare, but life-threatening type of ectopic pregnancy. an exact and early diagnosis of csp is very important for prognosis. the aim of the present study was to describe 4 women with csp and discuss their clinical presentations, diagnoses, and various management options along with the published literature. four women with a suspicion of csp or cervical pregnancy...

background:   objective: the aim of this study was to evaluate the expression of enos in the fts of women with tep.   materials and methods: in this case-control study, a total number of 30fts samples were obtained from three groups including: 10 fts of women that bearing an ep, 10 fts from the non-pregnant women at luteal phase of the menstrual cycle, and 10 fts of healthy pregnant women (n=10...

a case of cervical ectopic pregnancy in a 37 years old woman with history of two previous cesarean sections and one dilatation/curettage. the case was the advanced cervical pregnancy reported in iran, which diagnosed in 12 week of gestation by mri and finally treated by hysterectomy.

The implantation of a blastocyst into a receptive uterus is associated with a series of events, namely the attachment reaction followed by decidualization of the stroma. Previous studies established that the gene encoding heparin-binding EGF-like growth factor (HB-EGF) is expressed in the luminal epithelium solely at the site of blastocyst apposition preceding the attachment reaction. We report...

BACKGROUND Decidualization (differentiation) of the endometrial stromal cells during the secretory phase of the menstrual cycle is essential for successful implantation. Transforming Growth Factor β1 (TGFβ1) canonically propagates its actions via SMAD signalling. A role for TGFβ1 in decidualization remains to be established and published data concerning effects of TGFβ1 on markers of endometria...

background: ectopic pregnancy is one of the main problems in women in reproductive age that needs special attention and appropriate strategy should be managed. in some cases expectant management seems good strategy without any medicine or surgery and their possible side effects. but are the outcomes always the same? which outcomes should we expect? case: we have reported 2 patients whose ectopi...

BACKGROUND Successful embryonic implantation depends on a synchronized embryo-maternal dialogue. Chemokines, such as chemokine ligand 1 (CXCL1), play essential roles in the maternal reproductive tract leading to morphological changes during decidualization, mediating maternal acceptance towards the semi-allograft embryo and induction of angiogenesis. Chemokine binding to their classical G-prote...

It is well established that rat decidual tissue produces a PRL-like hormone(s) that binds to the PRL receptor on both the corpus luteum and the decidual cells and initiates profound changes in the endocrine milieu required for the establishment of pregnancy. The recent cloning of a decidual PRL-related protein (dPRP) prompted us 1) to determine whether the expression of this gene is triggered b...