economic dispatch with valve point effect and prohibited operating zones (pozs) is a non-convex and discontinuous optimization problem. harmony search (hs) is one of the recently presented meta-heuristic algorithms for solving optimization problems, which has different variants. the performances of these variants are severely affected by selection of different parameters of the algorithm. intel...

BACKGROUND AND AIMS The Roadmap concept is a therapeutic framework in chronic hepatitis B for the intensification of nucleoside analogue monotherapy based on early virologic response. The efficacy and safety of this approach applied to telbivudine treatment has not been investigated. METHODS A multinational, phase IV, single-arm open-label study (ClinicalTrials.gov ID NCT00651209) was underta...

This article is devoted to a detailed analysis and formation of guidelines for intensifying the development regional economic systems in theory creative economy under influence its characteristic intellectual innovative determinants. A brief description studied theoretical concept given, on basis which list key features that characterize built principles identified. The implementation basic pro...

This study examines whether and why a process of intensification of family relations took place during the long nineteenth century by investigating Dutch marriage couples’ selection of witnesses. The results show that during the period 1830-1950, lateral kin (siblings, siblings-in-law and cousins) were increasingly selected as marriage witnesses, at the expense of professional witnesses and pat...