DISCUSSION Molluscum contagious (MC) is a cutaneous infection described by Baterman in 1817. The etiologic agent is a DNA poxvirus. MC has been associated with other lesions like melanocytic nevus and/or epidermoid cyst (EC). The first case of MC in an EC was reported by Hodge et al in 1973. They reported a 33-year-old healthy man with a unique single lesion in the right thigh. The clinical dia...

The occurrence of the protected species Castor fiber L., which creates a network natural barriers for its own needs, may affect changes in water quality parameters. This study shows parameters (EC, BOD5, COD, TN, N-NH4, N-NO3, N-NO2, TP, P-PO4, Cl−, SO42−) small rivers eastern Poland. results were analysed using one-way and three-way ANOVA Tukey’s HSD post hoc test to identify significance habi...

Objective This study investigated the performance among four cardiac output (CO) monitoring techniques in comparison with reference method intermittent pulmonary artery thermodilution (iPATD) and their ability to diagnose fluid responsiveness (FR) during a modified passive leg raise (PLR M ) maneuver isoflurane-anesthetized dogs undergoing acute blood volume manipulations. The also examined sim...

Objectives To investigate the capability of computed-tomography (CT) radiomic features to predict the therapeutic response of Esophageal Carcinoma (EC) to chemoradiotherapy (CRT). Methods Pretreatment contrast-enhanced CT images of 49 EC patients (33 responders, 16 nonresponders) who received with CRT were retrospectively analyzed. The region of tumor was contoured by two radiologists. A tota...

We previously discovered a positive allosteric modulator (PAM) of the metabotropic glutamate receptor subtype 5 (mGlu(5)) termed 4 N-{4-chloro-2-[(1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl)methyl]phenyl}-2-hydroxybenzamide (CPPHA) that elicits receptor activation through a novel allosteric site on mGlu(5), distinct from the classical mGlu(5) negative allosteric modulator (NAM) MPEP allosteric site...

Management of intermediate-high risk early stage endometrial cancer (EC) can be challenging since a proportion these patients (pts) relapse and the role adjuvant chemotherapy (CT) is unclear. We aimed to evaluate CT for this population. This retrospective study evaluated pts with EC treated in single center from 2009 2021. Endpoints were overall survival (OS) disease free (DFS) according system...