نتایج جستجو برای: ebolavirus
تعداد نتایج: 1058 فیلتر نتایج به سال:
Since it first appeared as a clinical syndrome in Central Africa in the mid1970s, accompanied by isolation of the causative virus, Ebola virus disease has fascinated infectious disease clinicians, virologists, and epidemiologists because of the striking clinical syndrome exhibited by patients (which culminates in a hemorrhagic diathesis in approximately 35% of infected individuals) [1], high ca...
BACKGROUND Viral outbreaks, such as the 2014 ebolavirus, can spread rapidly and have complex evolutionary dynamics, including coinfection and bulk transmission of multiple viral populations. Genomic surveillance can be hindered when the spread of the outbreak exceeds the evolutionary rate, in which case consensus approaches will have limited resolution. Deep sequencing of infected patients can ...
animals in the Philippines: a review. J Infect Dis. 2011;204(Suppl 3):S757–60. http://dx.doi.org/10.1093/infdis/jir296 4. Negredo A, Palacios G, Vázquez-Morón S, González F, Dopazo H, Molero F, et al. Discovery of an ebolavirus-like filovirus in Europe. PLoS Pathog. 2011;7:e1002304. http://dx.doi.org/10.1371/ journal.ppat.1002304 5. Olival KJ, Islam A, Yu M, Anthony SJ, Epstein JH, Khan SA, et ...
Ebolaviruses are highly infectious pathogens that cause lethal Ebola virus disease (EVD) in humans and non-human primates (NHPs). Due to their high pathogenicity and transmissibility, as well as the potential to be misused as a bioterrorism agent, ebolaviruses would threaten the health of global populations if not controlled. In this review, we describe the origin and structure of ebolaviruses ...
When Ebola virus nucleoprotein (NP) is expressed in mammalian cells, it assembles into helical structures. Here, the recombinant NP helix purified from cells expressing NP was characterized biochemically and morphologically. We found that the recombinant NP helix is associated with non-viral RNA, which is not protected from RNase digestion and that the morphology of the helix changes depending ...
To determine geographic range for Ebola virus, we tested 276 bats in Bangladesh. Five (3.5%) bats were positive for antibodies against Ebola Zaire and Reston viruses; no virus was detected by PCR. These bats might be a reservoir for Ebola or Ebola-like viruses, and extend the range of filoviruses to mainland Asia.
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