Precocious puberty results mostly from the precocious activation of the gonadotropic axis. Although the age limits have recently been discussed, most physicians consider that onset of pubertal development before the age of 8 years in a girl or 9 years in a boy warrants at least a clinical and bone age evaluation by a paediatric endocrinologist. The major concern in precocious puberty is the und...

background. teenagers, a huge age group in developing countries, face a period with many physical, mental and social problems. appropriate health education concerning their periodic development is of importance in community health services. the present study performed a comparative assessment of subjects’ knowledge, attitude and practice, concerning puberty health programs. method. in an interv...

Puberty is governed by the secretion of gonadotropin releasing hormone (GnRH), but the roles and identities of upstream neuropeptides that control and time puberty remain poorly understood. Indeed, how various reproductive neural gene systems change before and during puberty, and in relation to one another, is not well-characterized. We detailed the daily pubertal profile (from postnatal day [P...

the age of criminal responsibility of children in the islamic penalties act has been determined as religious bulugh (puberty) nasab. according to this, criminal authorities hold girls criminally liable and punishable at 9 complete lunar years and boys at 15 complete lunar years. unfortunately, our legislator has set criminal responsibility of children based on sexual maturity; therefore, thousa...

Sexual precocity is considered to be present when indications of genital maturation become apparent in boys before the age of 10 years and in girls before the age of 8 years (Seckel, 1946). It is customary to divide these cases into two groups. In those with true precocious puberty maturation with spermatogenesis or ovulation has occurred in a normal manner, but at an abnormally early age; in t...

Sexual precocity is considered to be present when indications of genital maturation become apparent in boys before the age of 10 years and in girls before the age of 8 years (Seckel, 1946). It is customary to divide these cases into two groups. In those with true precocious puberty maturation with spermatogenesis or ovulation has occurred in a normal manner, but at an abnormally early age; in t...

During puberty, humans develop a later chronotype, exhibiting a phase-delayed daily rest/activity rhythm. The purpose of this study was to determine: 1) whether similar changes in chronotype occur during puberty in a laboratory rodent species, 2) whether these changes are due to pubertal hormones affecting the circadian timekeeping system. We tracked the phasing and distribution of wheel-runnin...

Inhibin B levels were measured in serum from 400 healthy Danish prepubertal, pubertal, and adolescent males, aged 6-20 yr, in a cross-sectional study using a recently developed immunoassay that is specific for inhibin B, the physiologically important inhibin form in men. In addition, serum levels of FSH, LH, testosterone, and estradiol levels were measured. Serum levels of inhibin B, FSH, LH, t...