INTRODUCTION Like a fingerprint, ear shape is a unique personal feature that should be reconstructed with a high fidelity during reconstructive surgery. Ear cartilage tissue engineering (TE) advantageously offers the possibility to use novel 3D manufacturing techniques to reconstruct the ear, thus allowing for a detailed auricular shape. However it also requires detailed patient-specific images...

OBJECTIVES We have previously demonstrated the immunomodulatory effects of physalins, secosteroids purified from Physalis angulata. Here we investigate the antileishmanial activity of physalins in vitro and in vivo in a model of cutaneous leishmaniasis. METHODS The antileishmanial activity of physalins B, D and F was tested in Leishmania-infected macrophage cultures. For the in vivo studies, ...

OBJECTIVES Otoplasty is a commonly performed surgical procedure that restores the ideal position of the pinna. Although the pinna is a well-recognized component of the auditory apparatus, no studies have assessed the audiological effects of this procedure. We sought to quantify the impact of pinna repositioning on speech intelligibility and reception. METHODS Eighteen adults with normal heari...

background: assisted reproductive techniques (art) are used with increasing frequency worldwide. the present research was conducted to determine the effects of art on hearing defects and ear abnormalities. materials and methods: n a descriptive, cross-sectional, non-randomized study, the status of hearing and ear abnormalities was assessed in 300 newborns conceived by art at royan institute, te...

The risk of complications of auricular correction is underestimated. There is around a 5% risk of early complications (haematoma, infection, fistulae caused by stitches and granulomae, allergic reactions, pressure ulcers, feelings of pain and asymmetry in side comparison) and a 20% risk of late complications (recurrences, telehone ear, excessive edge formation, auricle fitting too closely, narr...

Auricular hematoma is a frequent complication of blunt trauma to the auricle. These are usually caused by sports such as boxing and wrestling. Hematoma formation is within the space between perichondrium and cartilage on the anterior ear. Because the blood supply to cartilage is dependent on the perichondrium, infection and cartilaginous necrosis often complicate untreated auricular hematomas. ...

Keloids are most commonly located in the ears (44.4%), followed by the thorax (33.3%), and shoulders (7.4%) [1]. Keloids, along with hypertrophic scars, are caused by an aberration in the normal wound healing process and inflict great discomfort on the patient [2]. Abnormal scars may cause pain or pruritus, disturb the range of motion, diminish sensation, or cause aesthetic deformities that may...

OBJECTIVE To evaluate the relationships between temporal bone abnormalities and the severity of microtia in Japanese patients using objective grading systems. DESIGN Retrospective case series study conducted between 1992 and 2003. SETTING Academic, tertiary care, referral medical center. PATIENTS One hundred forty-two ears of 109 Japanese patients (85 male and 24 female patients; mean age...

OBJECTIVES To quantitatively analyzing the anatomic variants on temporal computed tomography (CT) in congenital external auditory canal stenosis (EACS), congenital aural atresia (CAA), and normal ear structure. METHODS Through a retrospective study, we analyzed 142 temporal high-resolution CT studies performed in 71 microtia patients. The following 6 parameters were compared among the three g...