نتایج جستجو برای: dyslipidemic

تعداد نتایج: 840  

Journal: :Nepalese heart journal 2023

Background and Aims: Cardiovascular Disease is the leading cause of death. Prevention cardiovascular disease major aim treatment anyone who has risk. Dyslipidemia lies in center Not only there difference pattern dyslipidemia response to statins different ethnic groups, mortality due race group. Atorvastatin Rosuvastatin are first line statins. This study carried out see how our population respo...

Journal: :Journal of medicinal chemistry 2015
Kentaro Futatsugi Daniel W Kung Suvi T M Orr Shawn Cabral David Hepworth Gary Aspnes Scott Bader Jianwei Bian Markus Boehm Philip A Carpino Steven B Coffey Matthew S Dowling Michael Herr Wenhua Jiao Sophie Y Lavergne Qifang Li Ronald W Clark Derek M Erion Kou Kou Kyuha Lee Brandon A Pabst Sylvie M Perez Julie Purkal Csilla C Jorgensen Theunis C Goosen James R Gosset Mark Niosi John C Pettersen Jeffrey A Pfefferkorn Kay Ahn Bryan Goodwin

The medicinal chemistry and preclinical biology of imidazopyridine-based inhibitors of diacylglycerol acyltransferase 2 (DGAT2) is described. A screening hit 1 with low lipophilic efficiency (LipE) was optimized through two key structural modifications: (1) identification of the pyrrolidine amide group for a significant LipE improvement, and (2) insertion of a sp(3)-hybridized carbon center in ...

Journal: :Breast care 2012
Betul Ekiz Bilir Neslihan Soysal Atile Bulent Bilir Sibel Guldiken Nermin Tuncbilek Fulya Oz Puyan Atakan Sezer Irfan Coskun

BACKGROUND Lymphocytic mastitis is a disease of premenopausal women, and its association with type 1 diabetes mellitus is the basis for its alternative name 'diabetic mastopathy'. It is a benign condition but must be considered in the differential diagnosis of breast cancer, especially in diabetic patients. CASE REPORT We present the case of an overweight 50-year-old dyslipidemic woman with m...

2011
Kasra Azarnoush Mario Manca Andrea Innorta Lionel Camilleri

The combination of an acute ventricular septal defect (VSD) and left ventricular aneurysm (LVA) is a rare, life-threatening complication which usually occurs within the first week following acute myocardial infarcttion (AMI). We describe the case of an apical VSD and LVA in a 77-year-old diabetic and dyslipidemic male patient after anterior AMI. The patient was an active smoker and had a histor...

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