The 1H and 13C NMR resonances for a novel distamycin conjugate, 3-[1-methyl-4-[1-methyl-4-[1-methyl-4-[N1 -[5methyl-2,4(1H,3H)pyrimidinedione]acetylamino]pyrrole-2-carboxamido]pyrrole-2-carboxamido]pyrrole-2carboxamido]propionamidine hydrochloride (1), were assigned, using the concerted application of oneand two-dimensional NMR techniques including nuclear Overhauser effect difference, DEPT, HM...

Termination of DNA replication in Bacillus subtilis involves the polar arrest of replication forks by a specific complex formed between the dimeric 29 kDa replication terminator protein (RTP) and DNA terminator sites. We have used NMR spectroscopy to probe the changes in 1H-15N correlation spectra of a 15N-labelled RTP.C110S mutant upon the addition of a 21 base pair symmetrical DNA binding sit...

This study aimed to use an existing ligand (imidazole)-assisted 1H-nuclear magnetic resonance (1H-NMR) spectroscopy protocol determine sulfate content of seaweed sulfated saccharides. Twenty samples – spanning nine species and multiple geographic locations were analyzed. Extracts obtained by immersing freeze-dried seaweeds in boiling water, followed alginate precipitation. Remaining supernatant...

Three new iridoid glucosides, 10-O-[(E)-cinnamoyl]-geniposidic acid, 10-O-[(E)-p-coumaroyl]-geniposidic acid, 10-O-[(E)-caffeoyl]-geniposidic acid and the known iridoid glucoside, 2'-O-[(E)-cinnamoyl]-mussaenosidic acid have been isolated from Avicennia marina. The structures were determined primarily by NMR spectroscopy. The assignment of NMR signals was performed by means of 1H-1H COSY, HMQC ...

A series of di- and trinucleating ligands with a 1,3,5-triethylbenzene core connected to N,N-bidentate tethers was synthesized. The ligands readily reacted with monuclear Rh and Pd precursors to give the corresponding di- and trinuclear complexes, which were characterized by using NMR and ESI mass spectroscopy. In the solid state, the trinuclear complexes with ligands having pyridylpyrazolyl te...

In this research an effective and appropriate method has been developed for one-pot synthesis of new N-phenyl fulleroisoxazoline using Fe3O4@SiO2 nanoparticles as a green magnetically recyclable catalyst. The prepared catalytic samples were characterized by XRD, SEM, FT-IR and VSM. The products have been characterized by physical and spectroscopic data such as IR, 1H NMR, 13C NMR, and MS analyses.

2-Phenoxy-1,3,2-diazaphospha-[3]ferrocenophane and related derivatives (oxide, sulfide, selenide) were prepared, characterized in solution by multinuclear magnetic resonance methods (1D and 2D 1H, 13C, 15N and 31P NMR) and in the solid state by X-ray structural analysis. The conformation of the 2-phenoxy derivative differs from that of the 2-tert-butyl compound. For further comparison, 2-R2,3-d...

This paper highlights the use of two-dimensional (2D) solid-state NMR correlation techniques to probe the chemical homogeneity of organically modified silicate networks. Specifically, 29Si{1H} heteronuclear correlation (HETCOR) NMR experiments have revealed the spatial proximity of the two types of Si units present in a gel obtained from co-hydrolysis of methyldiethoxysilane and triethoxysilane...

The data shown in this article are related to the subject of an article in Carbohydrate Polymers, entitled "Synthesis and characterization of chitosan alkyl urea" [1]. 1H NMR and 13C NMR spectra of chitosan n-octyl urea, chitosan n-dodecyl urea and chitosan cyclohexyl urea are displayed. The chemical shifts of proton and carbon of glucose skeleton in these chitosan derivatives are designated in...

We have investigated the dissolution performance of amorphous solid dispersions of poorly water-soluble bicalutamide in a Kollidon VA64 polymeric matrix as a function of the drug loading (5% vs. 30% bicalutamide). A combined suite of state-of-the-art analytical techniques were employed to obtain a clear picture of the drug release, including an integrated magnetic resonance imaging UV-Vis flow ...