Abstract Study question Does desogestrel an option for LH suppression during controlled ovarian stimulation oocyte vitrification? Summary answer This new did not affect FORT and, consequently, the number of collected oocytes vitrification. What is known already Traditionally, achieved by using a gonadotropin-releasing hormone (GnRH) analogue. However, improved cryopreservation techniques and fr...

It is well established that all non-hysterectomised women taking oestrogen replacement therapy should receive additional progestogen to reduce the incidence of endometrial hyperplasia1–3 and cancer.4 Progestogens are either added cyclically on a monthly (sequential), or 3monthly basis (tricyclic) or continuously (period-free or no bleed). Alternative combinations such as bimonthly,5 6monthly6 a...

BACKGROUND Endometriosis is a chronic inflammatory condition defined by the presence of glands and stroma outside the uterine cavity. It occurs in 7% to 10% of all women of reproductive age and may present as pain or infertility. The pelvic pain may be in the form of dysmenorrhoea, dyspareunia or pelvic pain. Initially a combination of estrogens and progestagens was used to create a pseudopregn...

It is well established that increased exposure to estradiol (E(2)) is an important risk factor for the genesis and evolution of breast tumors, most of which (approximately 95-97%) in their early stage are estrogen-sensitive. However, two thirds of breast cancers occur during the postmenopausal period when the ovaries have ceased to be functional. Despite the low levels of circulating estrogens,...

Abstract Study question 1. Is it beneficial to provide luteal phase support in each IUI cycle stimulated by oral ovulogens ? Summary answer Luteal with progesterone makes no significant difference clinical pregnancy rate ovulogen cycles. What is known already ART (assisted reproductive techniques) involves superovulation achieve the development of multiple follicles. This produces supraphysiolo...

Endocrine treatment of endometriosis is based upon the suggestion of Kistner that regression of endometriosis can be obtained by induction of pseudo-pregnancy with a combination of oestrogen and progestin (1). The 40-year history of conservative medical therapy of endometriosis demonstrates that many substances and their combinations have been tested, including low-dose oral contraceptives, pro...

Case report-Subjects-Three cases are described oflong-standing vaginal candidosis due to Candida glabrata. These had failed to respond to local and systemic antifungals. In each case the infecting strain appeared resistant to a range of azole drugs in vitro. Clinical course-Case one-This patient recovered following prolonged treatment with oral itraconazole in combination with oral and vaginal ...