Abstract The navigation and positioning subsystem offers important position information for an autonomous underwater vehicle (AUV) system. It plays a crucial role during the exploration operations of AUV. Many scholars research positioning. Various improved methods systems were presented. However, as diversity ocean environment, random drift gyroscope, error accumulation, variety tasks, other n...

Background: Wnt signaling causes phosphorylation of Dishevelled, but its functional significance is unclear. Result: Sites of Wnt-induced phosphorylation were mapped in Dvl2 and mutated to permit functional testing. Conclusion: Three CK1 phosphorylation sites in the C-terminal of Dvl2 account for the Wnt induced mobility shift and modulate signaling. Significance: Wnt-induced phosphorylation of...

The long-term stimulation of hyperglycemia greatly increases the incidence of vascular restenosis (RS) after angioplasty. Neointimal hyperplasia after vascular injury is the pathological cause of RS, but its mechanism has not been elucidated. MicroRNA-24 (miR-24) has low expression in the injured carotid arteries of diabetic rats. However, the role of miR-24 in the vascular system is unknown. I...

An increasing number of cellular signaling pathways utilize protein ubiquitination for activation of signaling cascades. In this issue of Molecular Cell, Maurice and colleagues demonstrate that nondegradative Lys63-linked polyubiquitin chains modulate Dishevelled (Dvl) activity upstream in the Wnt/beta-catenin signaling pathway.

Configuration and geometry of bracing systems affect the seismic performance of structures significantly. Recently, the current authors have introduced a new configuration for eccentric bracing of structural frames that may be assumed as the combination of inverted Y-type and rotated K-type EBFs. The resulted braced frame is called EBF-DVL, consisting of two vertical links attached together by ...