introduction: it has been reported the alkaline response of pancreas to duodenal acidification is partly mediated through duodenal release of h2s, but till now the effect of duodenal acidification on gastric h2s release has not been investigated. therefore, the present study designed to evaluate the effects of duodenal acidification on gastric h2s release and level of mrna expression of cystath...

During endoscopic treatment for duodenal neoplasm, hazardous complications such as perforation and bleeding sometimes occur owing to the anatomical characteristics of the duodenum [1–3]. Although surgical repair has been traditionally required for these complications, the procedure is invasive and complicated [4]. A currently available overthe-scope clip (OTSC; Ovesco Endoscopy, Tübingen, Germa...

Approximately, 10 to 20% of patients with peptic ulcer suffer a perforation of stomach or duodenum in which chemical peritonitis develop initially from gastric and duodenal secretion but in a few hours bacterial contamination superimpose the disease. The disease could be life-threatening, early diagnosis and treatment is extremely important. The mortality will increase up if perforation exists ...

Bouveret's syndrome is a rare variant of gallstone ileus with an overall incidence of 1-3%. It is a rare cause of gastric outlet obstruction resulting from the passage and impaction of a large gallstone through a cholecysto-duodenal fistula. A combination of diagnostic modalities is often required for a diagnosis. Management options include endoscopy and surgery. The most commonly performed pro...