conclusions although the patients carrying m204i mutation were more likely to show lack of responses to lam therapy, lam replacing by other nucleoside/tide analogs plus hbig maybe still effective in decreasing hepatitis b recurrence after liver transplantation. however, it is suggested that drug resistance test should be considered by clinicians during therapeutic management to avoid the follow...

background: drug abuse is a major health problem in many countries. noticing the different patterns of drug abuse in different areas, we evaluated the epidemiology of drug abuse and related factors in fars province, southern iran. materials and methods: in a one-year cross-sectional study, from march 21st, 2009 to 2010, all subjects referring to addiction treatment clinic of shiraz university w...

unintentional drug intoxication is still a major cause of morbidity and mortality in young children. in order to study the epidemiological pattern of childhood drug poisoning in golestan province, all cases diagnosed with poisoning from 1997 to 2002 in the only pediatric hospital in province were recruited. during this period 563 cases of poisoned children were hospitalized in taleqani hospital...

the production of experimentally induced drug resistance in the laboratory provides valuable opportunities for investigators to study the nature and genetics of drug resistance mechanisms to a given agent, patterns of cross resistance and the mode of action of drugs. at the beginning the continuous drug exposure was chosen as a standard procedure to produce drug— resistant strains of p. falcipa...

drug interaction may cause sever adverse drug reactions in patients. the high amounts of prescribed medication in hospitalized patients will cause higher incidence of drug interactions. therefore, the study of drug interactions in hospitalized patients seems to be worth. we have, studied drug interaction in internal and surgical units, in kashani hospital in shahrekord. factors included in this...

abstract background: seizure is a frequent and important finding in the field of clinical toxicology. almost all poisons and drugs can produce seizure. we have evaluated frequency and complications of drug-induced seizure in present study. methods: the present descriptive cross-sectional study was done on patients who were referred to baharloo hospital, tehran, iran, that had developed seizure ...

background and aims: acute drug poisoning is a major public health problem in the world.the aim of this study was to investigate the trends and characteristics of acute drug poisoning and to compare that with other poisonings in gorgan, iran. methods: this descriptive cross-sectional study was done from march 2008 to march 2015. data were obtained from medical records. stata software and pearso...

the aim is the study on the impact of pethedine 4 hours before labor on newborn. data was gathered based on the apgar scores in first and fifth minutes after birth. three groups of mothers were selected: without any use of pethedine, use of pethedine less than 4 hours before labor and use of pethedine more than 4 hours before labor. the data was analyzed by using computer programs. there was no...

Background: Drug-drug Interaction (DDI) among the elderly is one of the major healthcare challenges worldwide. The present study assessed the rates of DDI and inappropriate drug prescription among the elderly in Kashan City, Iran.  Methods: This descriptive-analytical study was designed, conducted, and reported according to the guideline of Strengthening the Reporting of Observational Studies ...