OBJECTIVE Drug use and receipt of highly active antiretroviral therapy (HAART) were assessed in HIV-infected persons from the Comprehensive Care Center (CCC; Nashville, TN) and Johns Hopkins University HIV Clinic (JHU; Baltimore, MD) between 1999 and 2005. METHODS Participants with and without injection drug use (IDU) history in the CCC and JHU cohorts were evaluated. Additional analysis of p...

Illicit drug use, and the associated health problems, is a frequent issue encountered by medical providers. Because of its salience as a piece of health care information, drug use history is often included in patient charts and presentations by house staff and medical students. However, if used and recorded inappropriately, drug use history can have significant long-lasting effects on the perce...

background: acquired immune deficiency syndrome (aids) was firstly reported from california and soon became a pandemic in the world.this disease poses seriousthreats to humans’ health.in this study, we intended to examine the characteristicsof hiv-positive patients whoreferred to the behavioral diseases consultation center (bdcc) in shiraz, iran.   methods : this was a cross-sectional descripti...

BACKGROUND This study was performed to evaluate the diagnostic accuracy of a pharmacovigilance algorithm in patients with 1 or more histories suggestive of drug hypersensitivity. METHODS We performed a retrospective analysis of a clinic case series. We analyzed patients with suspected clinical reactions of drug hypersensitivity. Patients with severe skin reactions were excluded. Patients with...

Although new invasive procedures for the treatment of migraine have evolved during the past decades, the application of invasive procedures for this indication is not new. In this review, the history of non-drug treatments for migraine is discussed. Historical texts by physicians known to have written on headache and migraine (hemicrania), well-known books by physicians from the main historical...

BACKGROUND The long term outcome of drug related liver disease is unknown. AIMS To study the natural history of histologically proved drug induced hepatotoxicity. METHODS 110 patients with liver biopsies coded either as drug induced liver disease or hepatitis/cholestasis of unknown aetiology were identified from hospital records 1978-1996. Review of case notes and histology identified 44 pa...

e19651 Background: Cancer patients (CP) are frequently exposed to polypharmacy, which may increase their risk for drug interactions. Our study aims were to 1) determine and compare the prevalence and clinical significance of potential drug interactions (PDI) in CP vs. non-cancer patients (NCP) and 2) identify clinical risk factors associated with PDI in CP. METHODS Self-reported prescription ...

From the Program in Infectious Disease and Social Change, Department of Global Health and Social Medicine, Harvard Medical School; the Division of Global Health Equity, Brigham and Women’s Hospital; and Partners in Health — all in Boston. Address reprint requests to Dr. Keshavjee at the Department of Global Health and Social Medicine, Harvard Medical School, 641 Huntington Ave., Boston, MA 0211...