Sir, A generalized pustular eruption in an adult may be the presenting feature of viral infections, drug eruptions, psoriasis, subcorneal pustular dermatosis or impetigo herpetiformis. Rarely, generalized pustulation is a manifestation of secondary syphilis. We present here a case of secondary syphilis with a dramatic generalized eruption of pustules followed by impetiginous lesions. The classi...

background: adverse cutaneous drug reactions (acdrs) are the most commonly reported adverse drug events. the causative drugs and clinical patterns of acdrs are different in various populations. this study was conducted to identify the clinical patterns, causative drugs and reasons for drug administration in patients hospitalized due to acdr. materials and methods: this retrospective study was c...

Cutaneous adverse effects of imatinib mesylate (Glivec) are common and various types of skin eruptions have been reported. We report here a 57-year-old man who presented with lichen planus-like lesions on his extremities and palmoplantar hyperkeratosis due to the use of imatinib mesylate for chronic myeloid leukaemia. The skin lesions improved after discontinuation of imatinib mesylate but re-a...

Adverse drug reactions (ADR) are among the most frequent problems encountered clinically and represent a common cause for hospitalization.Fixed drug eruptions are common cutaneous ADR.The aim of this study is to evaluate the drugs and the clinical pattern of drug induced Fixed Drug Eruptions (FDE), in a tertiary care hospital, in the southern region of Tamil Nadu. Sixty cases with established F...